Aziridine, 2-(1-methylethylidene)-1-[(1S)-1-phenylethyl]-

Base Information

Chemical Name:Aziridine, 2-(1-methylethylidene)-1-[(1S)-1-phenylethyl]-
CAS No.:504433-37-8
Molecular Formula:C13H17N
Molecular Weight:187.285
Hs Code.:
DSSTox Substance ID:DTXSID10462610
Nikkaji Number:J1.730.972B

Synonyms:504433-37-8;Aziridine, 2-(1-methylethylidene)-1-[(1S)-1-phenylethyl]-;DTXSID10462610

Suppliers and Price of Aziridine, 2-(1-methylethylidene)-1-[(1S)-1-phenylethyl]-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of Aziridine, 2-(1-methylethylidene)-1-[(1S)-1-phenylethyl]-

Chemical Property:

XLogP3:3.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:2
Exact Mass:187.136099547
Heavy Atom Count:14
Complexity:232

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C1=CC=CC=C1)N2CC2=C(C)C
Isomeric SMILES:C[C@@H](C1=CC=CC=C1)N2CC2=C(C)C

Technology Process of Aziridine, 2-(1-methylethylidene)-1-[(1S)-1-phenylethyl]-

There total 2 articles about Aziridine, 2-(1-methylethylidene)-1-[(1S)-1-phenylethyl]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: 504433-36-7
(S)-N-(2-bromo-3-methyl-2-butenyl)-1-phenylethylamine

: 504433-37-8
[(S)-1-phenylethyl]-2-(propan-2-ylidene)aziridine

Guidance literature:: With ammonia; sodium amide; for 0.5h;

Reference yield:

: 2627-86-3
(S)-1-phenyl-ethylamine

: 504433-37-8
[(S)-1-phenylethyl]-2-(propan-2-ylidene)aziridine

Guidance literature:: Multi-step reaction with 2 steps

1: 70 percent / potassium carbonate / 1,2-dichloro-benzene / 72 h / 160 °C

2: 89 percent / sodium amide; ammonia gas / 0.5 h

With ammonia; potassium carbonate; sodium amide; In 1,2-dichloro-benzene;

Reference yield: 80.0%

: 75-77-4
chloro-trimethyl-silane

: 504433-37-8
[(S)-1-phenylethyl]-2-(propan-2-ylidene)aziridine

: (1'S,3R)-2-isopropylidene-1-(1'-phenylethyl)-3-trimethylsilylaziridine

: (1'S,3S)-2-isopropylidene-1-(1'-phenylethyl)-3-trimethylsilylaziridine

Guidance literature:: [(S)-1-phenylethyl]-2-(propan-2-ylidene)aziridine; With N,N,N,N,-tetramethylethylenediamine; sec.-butyllithium; In tetrahydrofuran; cyclohexane; at -78 ℃;

chloro-trimethyl-silane; In tetrahydrofuran; cyclohexane; at -78 - 20 ℃;
DOI:10.1039/b303252c