2-Crotonyloxymethyl-2-cyclohexenone

Base Information

Chemical Name:2-Crotonyloxymethyl-2-cyclohexenone
CAS No.:106281-45-2
Molecular Formula:C11H14 O3
Molecular Weight:194.23
Hs Code.:2916190090
Nikkaji Number:J1.717.520C,J1.991.490I
ChEMBL ID:CHEMBL60020
Mol file:106281-45-2.mol

Synonyms:2-COMC;2-crotonyloxymethyl-2-cyclohexenone;2-crotonyloxymethyl-cyclohex-2-enone;COMC-6

Suppliers and Price of 2-Crotonyloxymethyl-2-cyclohexenone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 2-Crotonyloxymethyl-2-cyclohexenone

Chemical Property:

Vapor Pressure:0.000879mmHg at 25°C
Boiling Point:304.3°Cat760mmHg
Flash Point:132.4°C
PSA：43.37000
Density:1.088g/cm³
LogP:1.78510
XLogP3:1.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:194.094294304
Heavy Atom Count:14
Complexity:287

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC=CC(=O)OCC1=CCCCC1=O
Isomeric SMILES:C/C=C/C(=O)OCC1=CCCCC1=O

Technology Process of 2-Crotonyloxymethyl-2-cyclohexenone

There total 2 articles about 2-Crotonyloxymethyl-2-cyclohexenone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 623-68-7
crotonic anhydride

: 105956-40-9
2-(hydroxymethyl)cyclohex-2-en-1-one

: 106281-45-2
2-crotonyloxymethyl-2-cyclohexenone

Guidance literature:: With pyridine; dmap; In dichloromethane; at 20 ℃; for 2h;
DOI:10.1021/ol025650h

Reference yield:

: 930-68-7
cyclohexenone

: 106281-45-2
2-crotonyloxymethyl-2-cyclohexenone

Guidance literature:: Multi-step reaction with 2 steps

1: 64 percent / DMAP / tetrahydrofuran; H₂O / 20 h / 20 °C

2: 88 percent / DMAP; pyridine / CH₂Cl₂ / 2 h / 20 °C

With pyridine; dmap; In tetrahydrofuran; dichloromethane; water; 1: Baylis-Hillman reaction;
DOI:10.1021/ol025650h

Reference yield:

: 70-18-8
GLUTATHIONE

: 106281-45-2
2-crotonyloxymethyl-2-cyclohexenone

: 419564-05-9
2-glutathionylmethyl-2-cyclohexenone

Guidance literature:: With human placental glutathione transferase; In phosphate buffer; at 25 ℃; pH=6.5; Further Variations:; Reagents; Kinetics;
DOI:10.1021/ol025650h