2-(4-Methoxyphenyl)-4-methyl-1,3-dioxolane

Base Information

• Chemical Name: 2-(4-Methoxyphenyl)-4-methyl-1,3-dioxolane
• CAS No.: 6414-32-0
• Molecular Formula: C11H14 O3
• Molecular Weight: 194.23
• Hs Code.: 2932999099
• European Community (EC) Number: 229-117-7
• NSC Number: 74653
• UNII: XD1E01A8JR
• DSSTox Substance ID: DTXSID80863796
• Nikkaji Number: J207.025A
• Wikidata: Q27293782
• Mol file: 6414-32-0.mol

Synonyms:2-(4-Methoxyphenyl)-4-methyl-1,3-dioxolane;6414-32-0;Anisaldehyde propyleneglycol acetal;Anisaldehyde propylene glycol acetal;1,3-Dioxolane, 2-(4-methoxyphenyl)-4-methyl-;UNII-XD1E01A8JR;XD1E01A8JR;EINECS 229-117-7;NSC-74653;AI3-22604;NSC74653;SCHEMBL432453;FEMA NO. 4627;DTXSID80863796;Anis aldehydepropyleneglycol acetal 1;NSC 74653;AKOS006284332;(+/)-ANISALDEHYDE PROPYLENEGLYCOL ACETAL;2-(P-METHOXYPHENYL)-4-METHYL-1,3-DIOXOLANE;Q27293782;Methyl 4-(4-methyl-1,3-dioxolan-2-yl)phenyl ether #

Chemical Property of 2-(4-Methoxyphenyl)-4-methyl-1,3-dioxolane

Chemical Property:

• Vapor Pressure: 0.00421mmHg at 25°C
• Boiling Point: 287.8oC at 760 mmHg
• Flash Point: 95.5oC
• PSA: 27.69000
• Density: 1.085g/cm3
• LogP: 2.12910
• XLogP3: 1.7
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 2
• Exact Mass: 194.094294304
• Heavy Atom Count: 14
• Complexity: 175

Purity/Quality:

98%,99%, ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1COC(O1)C2=CC=C(C=C2)OC
• Uses: Anisic Aldehyde Propylene Glycol Acetal is a useful intermediate for organic synthesis and other chemical processes.

Technology Process of 2-(4-Methoxyphenyl)-4-methyl-1,3-dioxolane

There total 1 articles about 2-(4-Methoxyphenyl)-4-methyl-1,3-dioxolane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

propylene glycol (57-55-6,63625-56-9) + 4-methoxy-benzaldehyde (123-11-5) → 2-(4-methoxyphenyl)-4-methyl-1,3-dioxolane (6414-32-0)

Guidance literature:

With C₉H₁₉NO₃S*HO₄S^(1-)*0.5Zn⁽²⁺⁾; In cyclohexane; Dean-Stark; Reflux;

DOI:10.14233/ajchem.2015.17494

Reference yield: 6.0%

2-(4-methoxyphenyl)-4-methyl-1,3-dioxolane (6414-32-0) → 1-((4-methoxybenzyl)oxy)propan-2-ol + 2-[(4-methoxyphenyl)methoxy]propan-1-ol

Guidance literature:

With tri-n-butyl-tin hydride; magnesium bromide; In dichloromethane; at 20 ℃; for 0.166667h;

DOI:10.1016/S0040-4039(00)01017-0

upstream raw materials:

propylene glycol

4-methoxy-benzaldehyde

Refernces

• 1、 Jacques, Sylvain A.,Leriche, Geoffray,Mosser, Michel,Nothisen, Marc,Muller, Christian D.,Remy, Jean-Serge,Wagner, Alain. "From solution to in-cell study of the chemical reactivity of acid sensitive functional groups: A rational approach towards improved cleavable linkers for biospecific endosomal release". supporting information. p. 4794 - 4803. Retrieved 2016/06/13.
• 2、 Liang, Xuezheng. "Synthesis of novel solid acidic ionic liquid polymer and its catalytic activities". . p. 724 - 729. Retrieved 2014/01/23.