9-Ethyl-3-nitrocarbazole

Base Information

• Chemical Name: 9-Ethyl-3-nitrocarbazole
• CAS No.: 86-20-4
• Molecular Formula: C14H12N2O2
• Molecular Weight: 240.261
• Hs Code.: 2933990090
• European Community (EC) Number: 201-655-7
• NSC Number: 17817
• UNII: 00X39KP0AS
• DSSTox Substance ID: DTXSID0044995
• Nikkaji Number: J36.856C
• Wikidata: Q27231385
• ChEMBL ID: CHEMBL1366879
• Mol file: 86-20-4.mol

Synonyms:9-Ethyl-3-nitrocarbazole;86-20-4;9-Ethyl-3-nitro-9H-carbazole;3-Nitro-N-Ethyl carbazole;3-Nitro-N-ethylcarbazole;9H-Carbazole, 9-ethyl-3-nitro-;3-Nitro-9-ethylcarbazole;Carbazole, 9-ethyl-3-nitro-;n-Ethyl-3-Nitrocarbazole;UNII-00X39KP0AS;9-ethyl-3-nitro-9H-carbazol;00X39KP0AS;DTXSID0044995;EINECS 201-655-7;NSC 17817;NSC-17817;NSC17817;Piperilatehydrochloride;Oprea1_271225;MLS001018110;SCHEMBL149167;3-Nitro-9-ethyl-9H-carbazole;CHEMBL1366879;DTXCID8024995;6-NITRO-9-ETHYLCARBAZOLE;9-Ethyl-3-nitrocarbazole, 98%;HMS2640P13;9-Ethyl-3-nitro-9H-carbazole #;Tox21_301272;MFCD00022215;AKOS001030159;AKOS015916654;CCG-253850;CAS-86-20-4;NCGC00246000-01;NCGC00256185-01;AC-18965;AS-14545;SMR000354314;CS-0204377;FT-0631405;E85384;A841576;W-109312;Q27231385;Z56759381

Chemical Property of 9-Ethyl-3-nitrocarbazole

Chemical Property:

• Appearance/Colour: white crystalline powder
• Vapor Pressure: 1.95E-05mmHg at 25°C
• Melting Point: 128-130 °C(lit.)
• Refractive Index: 1.654
• Boiling Point: 362.3 °C at 760 mmHg
• Flash Point: 172.9 °C
• PSA: 50.75000
• Density: 1.27 g/cm³
• LogP: 4.24580
• XLogP3: 3.5
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• Exact Mass: 240.089877630
• Heavy Atom Count: 18
• Complexity: 328

Purity/Quality:

99.0% ^*data from raw suppliers

9-Ethyl-3-nitro-9H-carbazole ^*data from reagent suppliers

Safty Information:

• Safety Statements: 22-24/25

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: CCN1C2=C(C=C(C=C2)[N+](=O)[O-])C3=CC=CC=C31

Technology Process of 9-Ethyl-3-nitrocarbazole

There total 15 articles about 9-Ethyl-3-nitrocarbazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

ethyl bromide (74-96-4) + 3-Nitro-carbazol (3077-85-8) → 9-ethyl-3-nitro-carbazole (86-20-4)

Guidance literature:

3-Nitro-carbazol; With tetrabutylammomium bromide; sodium hydride; In tetrahydrofuran; for 0.166667h;

ethyl bromide; In tetrahydrofuran; for 0.166667h;

DOI:10.1016/j.tet.2013.07.040

Reference yield: 89.0%

N-ethylcarbazole (86-28-2) → 9-ethyl-3-nitro-carbazole (86-20-4)

Guidance literature:

With nitric acid; In acetic acid; at 23 ℃; for 6h;

Reference yield: 42.0%

acetamido-3 ethyl-9 nitro-6 carbazole (80776-24-5) → 9-ethyl-3-nitro-carbazole (86-20-4)

Guidance literature:

With hydrogenchloride; In ethanol; for 1.5h; Heating;

upstream raw materials:

ethyl bromide

3-Nitro-carbazol

diethyl sulfate

ethyl iodide

Downstream raw materials:

3-azido-9-ethyl-9H-carbazole

Refernces

• 1、 Wang, Wei-Dong,Hu, Yang,Li, Qiao,Hu, Sheng-Li. "A carbazole-based turn-on fluorescent probe for the detection of hydrazine in aqueous solution". . p. 206 - 211. Retrieved 2018/04/02.
• 2、 Rennison, David,Gueret, Stephanie M.,Laita, Olivia,Bland, Ross J.,Sutherland, Ian A.,Boddy, Ian K.,Brimble, Margaret A.. "Substituted Carbazoles-A New Class of Anthelmintic Agent". . p. 1268 - 1276. Retrieved 2016/11/25.