PYRIDINE-2-YL DIPHENYLMETHANOL

Base Information

• Chemical Name: PYRIDINE-2-YL DIPHENYLMETHANOL
• CAS No.: 19490-90-5
• Molecular Formula: C18H15NO
• Molecular Weight: 261.323
• Hs Code.: 2933399090
• Mol file: 19490-90-5.mol

Synonyms:NSC 10796;NSC525213;a,a-Diphenyl-2-pyridinemethanol;a,a-Diphenyl-2-pyridylmethanol;Diphenyl(2-pyridyl)carbinol;Diphenyl(2-pyridyl)methanol;Diphenyl(pyridin-2-yl)methanol;

Chemical Property of PYRIDINE-2-YL DIPHENYLMETHANOL

Chemical Property:

• Vapor Pressure: 5.49E-08mmHg at 25°C
• Refractive Index: 1.626
• Boiling Point: 425.2 °C at 760 mmHg
• Flash Point: 210.9 °C
• PSA: 33.12000
• Density: 1.169 g/cm³
• LogP: 3.36580

Purity/Quality:

99% ^*data from raw suppliers

ALPHA,ALPHA-DIPHENYL-2-PYRIDINEMETHANOL Aldrich ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of PYRIDINE-2-YL DIPHENYLMETHANOL

There total 33 articles about PYRIDINE-2-YL DIPHENYLMETHANOL which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

2-(diphenylmethoxy)-pyridine → diphenyl(2-pyridyl)methanol (19490-90-5)

Guidance literature:

With lithium diisopropyl amide; In tetrahydrofuran; at 20 ℃; Inert atmosphere;

DOI:10.1021/jo901707x

Reference yield: 96.0%

2-(diphenyltrimethylsiloxymethyl)-pyridine (120809-62-3) → diphenyl(2-pyridyl)methanol (19490-90-5)

Guidance literature:

pyridinium trifluroacetate; In ethanol; for 24h; Heating;

DOI:10.1016/S0040-4020(01)85961-5

Reference yield: 95.0%

benzophenone (119-61-9) → diphenyl(2-pyridyl)methanol (19490-90-5)

Guidance literature:

2-bromo-pyridine; With n-butyllithium; In tetrahydrofuran; at -70 ℃; for 2.33333h;

benzophenone; In tetrahydrofuran; at -70 - 20 ℃; for 5.5h;

upstream raw materials:

pyridine

benzophenone

2-Picolinic acid

phenyl(pyridin-2-yl)methanone

Downstream raw materials:

10-phenylpyrido[1,2-a]indole

Refernces

• 1、 Jaoul, Arnaud,Yang, Yan,Casaretto, Nicolas,Clavaguéra, Carine,Maron, Laurent,Nocton, Grégory. "Atom economical coupling of benzophenone and N-heterocyclic aromatics with SmI2". . p. 11875 - 11878. Retrieved 2020.
• 2、 -. "Green synthesis method of polyaryl substituted methanol". Paragraph 0127-0131; 0252-0256. . Retrieved 2021/04/17.