1H-Pyrazole-5-carboxamide, 1-(3-amino-1,2-benzisoxazol-5-yl)-N-[4-[2-[[[(1,1-dimethylethyl)dimethyl silyl]oxy]methyl]-1H-imidazol-1-yl]-2-fluorophenyl]-3-(trifluoromethyl)-

Base Information

Chemical Name:1H-Pyrazole-5-carboxamide, 1-(3-amino-1,2-benzisoxazol-5-yl)-N-[4-[2-[[[(1,1-dimethylethyl)dimethyl silyl]oxy]methyl]-1H-imidazol-1-yl]-2-fluorophenyl]-3-(trifluoromethyl)-
CAS No.:540510-50-7
Molecular Formula:C28H29F4N7O3Si
Molecular Weight:615.662
Hs Code.:

1H-Pyrazole-5-carboxamide,
1-(3-amino-1,2-benzisoxazol-5-yl)-N-[4-[2-[[[(1,1-dimethylethyl)dimethyl
silyl]oxy]methyl]-1H-imidazol-1-yl]-2-fluorophenyl]-3-(trifluoromethyl)-

Synonyms:

Suppliers and Price of 1H-Pyrazole-5-carboxamide, 1-(3-amino-1,2-benzisoxazol-5-yl)-N-[4-[2-[[[(1,1-dimethylethyl)dimethyl silyl]oxy]methyl]-1H-imidazol-1-yl]-2-fluorophenyl]-3-(trifluoromethyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 1H-Pyrazole-5-carboxamide, 1-(3-amino-1,2-benzisoxazol-5-yl)-N-[4-[2-[[[(1,1-dimethylethyl)dimethyl silyl]oxy]methyl]-1H-imidazol-1-yl]-2-fluorophenyl]-3-(trifluoromethyl)-

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 1H-Pyrazole-5-carboxamide, 1-(3-amino-1,2-benzisoxazol-5-yl)-N-[4-[2-[[[(1,1-dimethylethyl)dimethyl silyl]oxy]methyl]-1H-imidazol-1-yl]-2-fluorophenyl]-3-(trifluoromethyl)-

There total 9 articles about 1H-Pyrazole-5-carboxamide, 1-(3-amino-1,2-benzisoxazol-5-yl)-N-[4-[2-[[[(1,1-dimethylethyl)dimethyl silyl]oxy]methyl]-1H-imidazol-1-yl]-2-fluorophenyl]-3-(trifluoromethyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 53.0%

: 540510-50-7
N-[4-[(2-t-butyldimethylsilyloxymethyl)-1H-imidazol-1-yl]-2-fluorophenyl]-1-(3-amino-1,2-benzisoxazol-5-yl)-3-(trifluoromethyl)-1H-pyrazole-5-carboxamide

Guidance literature:

Reference yield:

: 540510-49-4
N-[4-[(2-tert-butyldimethylsilyloxymethyl)-1H-imidazol-1-yl]-2-fluorophenyl]-1-(3-cyano-4-fluorophenyl)-3-(trifluoromethyl)-1H-pyrazole-5-carboxamide

: 540510-50-7
N-[4-[(2-t-butyldimethylsilyloxymethyl)-1H-imidazol-1-yl]-2-fluorophenyl]-1-(3-amino-1,2-benzisoxazol-5-yl)-3-(trifluoromethyl)-1H-pyrazole-5-carboxamide

Guidance literature:: With acetylhydroxamic acid; potassium carbonate; In N,N-dimethyl-formamide; at 20 ℃; for 12h;
DOI:10.1021/jm0497949

Reference yield:

: 540510-47-2
1-(4-amino-3-fluorophenyl)-2-hydroxymethylimidazole

: 540510-50-7
N-[4-[(2-t-butyldimethylsilyloxymethyl)-1H-imidazol-1-yl]-2-fluorophenyl]-1-(3-amino-1,2-benzisoxazol-5-yl)-3-(trifluoromethyl)-1H-pyrazole-5-carboxamide

Guidance literature:: Multi-step reaction with 3 steps

1: 67 percent / Et₃N / dimethylformamide / 12 h / 20 °C

2: 0.48 g / DMAP / CH₂Cl₂ / 12 h / 20 °C

3: acetohydroxamic acid; aq. K₂CO₃ / dimethylformamide / 12 h / 20 °C

With dmap; acetylhydroxamic acid; potassium carbonate; triethylamine; In dichloromethane; N,N-dimethyl-formamide;
DOI:10.1021/jm0497949