5-nitro-2-phenoxybenzonitrile

Base Information

• Chemical Name: 5-nitro-2-phenoxybenzonitrile
• CAS No.: 63707-35-7
• Molecular Formula: C13H8 N2 O3
• Molecular Weight: 240.21
• Hs Code.: 2926909090
• Mol file: 63707-35-7.mol

Synonyms:2-Cyano-4-nitrophenylphenyl ether

Chemical Property of 5-nitro-2-phenoxybenzonitrile

Chemical Property:

• Vapor Pressure: 2.82E-05mmHg at 25°C
• Boiling Point: 356.9°C at 760 mmHg
• Flash Point: 169.7°C
• PSA: 78.84000
• Density: 1.34g/cm³
• LogP: 3.78198

Purity/Quality:

98%min ^*data from raw suppliers

5-Nitro-2-phenoxybenzonitrile ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 5-nitro-2-phenoxybenzonitrile

There total 7 articles about 5-nitro-2-phenoxybenzonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-chloro-3-cyanonitrobenzene (16588-02-6) + phenol (108-95-2,27073-41-2) → 2-cyano-4-nitrophenyl phenyl ether (63707-35-7)

Guidance literature:

With sodium ethanolate;

Reference yield:

sodium 4-aminophenolate (15267-98-8) + 4-chlorobenzonitrile (100-00-5) → 2-cyano-4-nitrophenyl phenyl ether (63707-35-7)

Guidance literature:

Reference yield:

2-fluoro-5-nitrobenzonitrile (17417-09-3) + phenol (108-95-2,27073-41-2) → 2-cyano-4-nitrophenyl phenyl ether (63707-35-7)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; at 80 ℃; for 2h;

DOI:10.1021/acs.jmedchem.7b01530

upstream raw materials:

4-chloro-3-cyanonitrobenzene

phenol

2-Chlorobenzonitrile

sodium 4-aminophenolate

Downstream raw materials:

N-(2-Cycano-4-nitrophenyl)-n-butylamin

5-amino-2-phenoxy-benzonitrile