15267-98-8

Upstream product

• 123-30-8 4-amino-phenol 
• 100-02-7 4-nitro-phenol 
• 103-90-2 4-acetaminophenol 
• 824-78-2 4-nitrophenol sodium salt 
• 6119-34-2 p-aminophenoxyl radical 

Downstream Products

• 6149-33-3 4-(4-nitrophenoxy)aniline 
• 111963-41-8 para-dimethylphosphinylmethyleneoxyaniline 
• 516526-32-2 4-(7-benzyloxy-6-methoxyquinolin-4-yloxy)aniline 
• 63707-35-7 2-cyano-4-nitrophenyl phenyl ether 
• 426209-95-2 [(CH₂CH₃)4N][W(OC₆H₄-p-NH₂)(1,2-diphenylethylene-1,2-dithiolate)2] 
• 426210-05-1 [(CH₂CH₃)4N][W(OC₆H₄-p-NH₂)(S₂C₂(C₆H₄-p-CH₃)2)2] 
• 426209-62-3 [(CH₂CH₃)4N][W(OC₆H₄-p-NH₂)(S₂C₂(C₆H₄-p-Br)2)2] 
• 426209-80-5 [(CH₂CH₃)4N][W(OC₆H₄-p-NH₂)(S₂C₂(C₆H₄-p-F)2)2] 
• 426210-16-4 [(CH₂CH₃)4N][W(OC₆H₄-p-NH₂)(S₂C₂(C₆H₄-p-OCH₃)2)2] 
• 13522-32-2 N,N-Dimethyl-thiocarbamidsaeure-O-(4-amino-phenylester) 
• 2676-59-7 bis(3,4-diaminophenyl)ether 
• 3070-87-9 N-[4-(4-acetylamino-3-nitrophenoxy)-2-nitrophenyl]acetamide 
• 3070-86-8 N-[4-(4-acetylaminophenoxy)phenyl]acetamide 
• 2687-40-3 4-nitrophenyl 4'-acetamidophenyl ether 

Relevant academic research and scientific papers

Highly porous palladium nanodendrites: Wet-chemical synthesis, electron tomography and catalytic activity

A simple procedure to obtain highly porous hydrophilic palladium nanodendrites in one-step is described. The synthetic strategy is based on the thermal reduction of a Pd precursor in the presence of a positively charged polyelectrolyte such as polyethylenimine (PEI). Advanced electron microscopy techniques combined with X-ray diffraction (XRD), thermogravimetry and BET analysis demonstrate the polycrystalline nature of the nanodendrites as well as their high porosity and active surface area, facilitating a better understanding of their unique morphology. Besides, catalytic studies performed using Raman scattering and UV-Vis spectroscopies revealed that the nanodendrites exhibit a superior performance as recyclable catalysts towards hydrogenation reaction compared to other noble metal nanoparticles.

Dry photochemical synthesis of hydrotalcite, γ-Al2O 3 and TiO2 supported gold nanoparticle catalysts

Gold nanoparticles (AuNP) supported on hydrotalcite, γ-Al 2O3 and TiO2 P25 have been prepared photochemically under mild conditions using ketyl radicals as the primary reducing agent; these nanocomposites were prepared directly in the solid phase. Such dry, solventless methods are attractive from an environmental perspective. The composite materials were successfully characterized using diffuse reflectance UV-visible spectroscopy, SEM, TEM, X-ray diffraction spectroscopy (XRD) and X-ray photoelectron spectroscopy (XPS). The supported AuNP were predominantly spherical and ranged in size from 20-140 nm depending on the support and the percent Au loading, indicating the potential applications of these particles as photocatalysts. The catalytic activity of the supported AuNP was evaluated using the well-studied reduction of 4-nitrophenol. UV-visible spectroscopy was used to monitor the reaction and illustrated the ability of these easily prepared AuNP composites to act has heterogeneous catalysts. The role of percent Au loading and type of support on the catalytic activity of supported AuNP was also investigated. Composites with relatively large AuNP may hold promise as efficient catalysts in plasmon-mediated light-driven reactions.

Photoluminescence as a valuable tool in the optical characterization of acetaminophen and the monitoring of its photodegradation reactions

In this work, new evidence for the photodegradation reactions of acetaminophen (AC) is reported by photoluminescence (PL), Raman scattering and FTIR spectroscopy. Under excitation wavelength of 320 nm, AC shows a PL band in the spectral range of 340–550 nm, whose intensity decreases by exposure to UV light. The chemical interaction of AC with the NaOH solutions, having the concentration ranging between 0.001 and 0.3 M, induces a gradual enhancement of the photoluminescence excitation (PLE) and PL spectra, when the exposure time of samples at the UV light increases until 140 min, as a result of the formation of p-aminophenol and sodium acetate. This behavior is not influenced by the excipients or other active compounds in pharmaceutical products as demonstrated by PLE and PL studies. Experimental arguments for the obtaining of p-aminophenol and sodium acetate, when AC has interacted with NaOH, are shown by Raman scattering and FTIR spectroscopy.

Silver nanoparticles stabilized by a polyaminocyclodextrin as catalysts for the reduction of nitroaromatic compounds

Silver nanoparticles stabilized by means of poly-(6-N,N-dimethyl-propylenediamino)-(6-deoxy)-β-cyclodextrin were synthesized, characterized by different techniques (UV-vis spectroscopy, Dynamic Light Scattering, High Resolution Transmission Electron Microscopy, Fourier-transform IR Spectroscopy) and used as catalysts for the reduction of various nitrobenzene derivatives with sodium borohydride. The nanocomposites obtained appear to have an organized structure, with a metal core surrounded by a layer-structured coating shell. Kinetic data, rationalized in terms of a modified Langmuir-Hinshelwood model, evidenced a non-linear dependence of the reaction rate on the concentration of the catalyst. This was explained on the grounds of the catalytic activity of differently covered catalyst areas. Careful analysis of kinetic data, in particular the effect of the para substituent on the nitroarene structure and the trends of the induction period observed at the beginning of the reaction, provided with interesting insights on the reaction course, and brought us to critically reconsider several mechanistic ideas reported in previous literature.

QUINOLINE DERIVATIVES AND QUINAZOLINE DERIVATIVES INHIBITING AUTOPHOSPHORYLATION OF Flt3 AND MEDICINAL COMPOSITIONS CONTAINING THE SAME

An objective of the present invention is to provide compounds and pharmaceticals useful for the treatment of disease where the inhibition of autophosphorylation of FMS-like tyrosine kinase 3(Flt3) is therapeutically effective. The present invention relates to a pharmaceutical composition for use in the treatment or prevention of diseases where the inhibition of autophosphorylation of Flt3 therapeutically or prophylactically effective, which comprises a compound represented by formula (I) or a pharmaceutically acceptable salt or solvate thereof: wherein X represents CH or N; Z represents O or S; R1, R2, and R3 represent H, OH, or optionally substituted alkoxy; R4 represents H; R5, R6, R7, and R8 represent H, Hal, alkyl or the like; and R9 represents, e.g., alkyl substituted by t-butyl or the like.

Reduction of the nitro group on palladium-containing membrane catalysts in alkaline solution

Reduction of sodium p-nitrophenolate on Pd/ceramic carrier, Pd/cation-exchange resin, and Pd/glass membrane catalysts was studied in 0.1 N NaOH. Electrode activity was found to be determined by the polarizing current density or the electrode potential val

Free Radical Combination Reactions Involving Phenoxyl Radicals

The rates of phenoxyl radical reactions with the superoxide anion radical, O2.-, a peroxyl radical, HOC(CH3)2CH2OO., and an alkyl radical, HOC(CH3)2CH2., in aqueous solution have been measured for 15 different phenoxyl radicals by means of pulse radiolysis.In addition, the one-electron reduction potentials of 10 phenoxyl radicals have been determined.The fraction of electron transfer in the reaction of phenoxyl radicals with O2.- was determined by analysis of γ-irradiated samples.The experimental data can be accommodated by the Marcus theory for electron transfer, with the reorganization energy λ0 = 155 kJ/mol for the reaction between O2.- and phenoxyl radicals.

HYDROGENATION OF SODIUM p-NITROPHENOLATE ON PALLADIUM AND NICKEL MEMBRANES.

With the aim of replacing costly palladium by cheaper nickel, we compared the catalytic activities of palladium and nickel membranes in hydrogenation of sodium p-nitrophenolate in 0. 1 N NaOH at temperatures in the range (20-70 degree ). Sodium p-nitrophe

Reduction of Sodium p-Nitrophenate on a Pd/Carbon Filament Membrane in Alkaline Solutions

We have studied the hydrogenation of sodium p-nitrophenate on a Pd/carbon filament membrane in a 0.1 N NaOH solution.The yield of amine can be controlled not only through the cathodic potential or the current on the polarisation side of the membrane but a