5-OXO-TETRAHYDROCARBAZOLE ETHYLENE KETAL

Base Information

• Chemical Name: 5-OXO-TETRAHYDROCARBAZOLE ETHYLENE KETAL
• CAS No.: 54621-12-4
• Molecular Formula: C14H15NO2
• Molecular Weight: 229.279
• Mol file: 54621-12-4.mol

Synonyms:thiadiazine;3,3-ethylenedioxy-1,2,3,4-tetrahydrocarbazole;Milneb;thiadiazine radical;Sanipa;Thiadiazin;Du Pont fungicide 328;Banlate;3,3-ethylenedioxy-2,3,4,9-tetrahydrocarbazole;Du Pont 328;Fungicide 328;

Chemical Property of 5-OXO-TETRAHYDROCARBAZOLE ETHYLENE KETAL

Chemical Property:

• PSA: 34.25000
• LogP: 2.39970

Purity/Quality:

99% ^*data from raw suppliers

1,2,4,9-Tetrahydrospiro[carbazole-3,2'-[1,3]dioxolane] 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 5-OXO-TETRAHYDROCARBAZOLE ETHYLENE KETAL

There total 8 articles about 5-OXO-TETRAHYDROCARBAZOLE ETHYLENE KETAL which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

cyclohexanedione monoethylene ketal (4746-97-8) + o-chloroaniline (95-51-2) → 1,2,4,9-tetrahydrospiro[3H-carbazole-3,2*-[1,3]doxolane] (54621-12-4)

Guidance literature:

With potassium phosphate; magnesium sulfate; acetic acid; bis(tri-t-butylphosphine)palladium⁽⁰⁾; In N,N-dimethyl acetamide; at 90 ℃; for 2h;

DOI:10.1002/anie.200460122

Reference yield: 94.0%

cyclohexanedione monoethylene ketal (4746-97-8) + phenylhydrazine (100-63-0) → 1,2,4,9-tetrahydrospiro[3H-carbazole-3,2*-[1,3]doxolane] (54621-12-4)

Guidance literature:

In ethylene glycol; at 190 ℃; for 18h;

DOI:10.3987/COM-14-S(K)19

Reference yield: 94.0%

cyclohexanedione monoethylene ketal (4746-97-8) + Azobenzene (1227476-15-4) → 1,2,4,9-tetrahydrospiro[3H-carbazole-3,2*-[1,3]doxolane] (54621-12-4)

Guidance literature:

With 4,4'-bipyridine; 2-(5,5-dimethyl-1,3,2-dioxaborinan-2-yl)-5,5-dimethyl-1,3,2-dioxaborinane; In benzene-d6; at 100 ℃; for 24h; Inert atmosphere; Glovebox;

DOI:10.1021/acs.joc.0c02661

upstream raw materials:

1,4-dioxa-spiro[4.5]decan-8-one phenylhydrazone

cyclohexanedione monoethylene ketal

2-iodophenylamine

o-chloroaniline