N-(Benzyloxy)-L-phenylalanine

Base Information

Chemical Name:N-(Benzyloxy)-L-phenylalanine
CAS No.:54837-24-0
Molecular Formula:C16H17NO3
Molecular Weight:271.31100
Hs Code.:
DSSTox Substance ID:DTXSID30707777
Nikkaji Number:J488.486H
Wikidata:Q82641728
Mol file:54837-24-0.mol

Synonyms:N-(Benzyloxy)-L-phenylalanine;54837-24-0;N-Benzyloxy-L-phenylalanine;SCHEMBL6130478;DTXSID30707777

Suppliers and Price of N-(Benzyloxy)-L-phenylalanine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of N-(Benzyloxy)-L-phenylalanine

Chemical Property:

PSA：58.56000
LogP:2.79460
XLogP3:0.6
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:7
Exact Mass:271.12084340
Heavy Atom Count:20
Complexity:283

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)CC(C(=O)O)NOCC2=CC=CC=C2
Isomeric SMILES:C1=CC=C(C=C1)C[C@@H](C(=O)O)NOCC2=CC=CC=C2

Technology Process of N-(Benzyloxy)-L-phenylalanine

There total 1 articles about N-(Benzyloxy)-L-phenylalanine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 16503-53-0
2-bromo-3-phenylpropanoic acid

: 622-33-3
N-benzyloxyamine

: 54837-24-0
N-benzyloxy-DL-phenylalanine

Guidance literature:: In ethanol; Heating;
DOI:10.1016/S0040-4020(01)97040-1

Reference yield: 88.0%

: 54837-24-0
N-benzyloxy-DL-phenylalanine

: 6066-82-6
1-hydroxy-pyrrolidine-2,5-dione

: 2-Benzyloxyamino-3-phenyl-propionic acid 2,5-dioxo-pyrrolidin-1-yl ester; hydrochloride

Guidance literature:: With dicyclohexyl-carbodiimide; In tetrahydrofuran; 1) 0 deg C, 1 h, 2) 20 h, refrigerator;
DOI:10.1246/bcsj.57.2456

Reference yield:

: 54837-24-0
N-benzyloxy-DL-phenylalanine

: (2-{[2-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-acetyl]-hydroxy-amino}-3-phenyl-propionylamino)-acetic acid methyl ester

Guidance literature:: Multi-step reaction with 4 steps

1: 88 percent / N,N-dicyclohexylcarbodiimide / tetrahydrofuran / 1) 0 deg C, 1 h, 2) 20 h, refrigerator

2: 85 percent / (C₂H₅)3N / CHCl₃ / 1) 0 deg C, 2 h, 2) room temperature, 24 h

3: 91 percent / (C₂H₅)3N / dimethylformamide / 24 h / -5 °C / oth. N-benzyloxyamino acids

4: 88 percent / H₂ / 10percentPd on carbon / methanol / 24 h / 30 °C

With hydrogen; triethylamine; dicyclohexyl-carbodiimide; 10% palladium on active carbon; In tetrahydrofuran; methanol; chloroform; N,N-dimethyl-formamide;
DOI:10.1246/bcsj.57.2456