1,4-dimethyl-1,2,3,4-tetrahydroquinoxaline

Base Information

• Chemical Name: 1,4-dimethyl-1,2,3,4-tetrahydroquinoxaline
• CAS No.: 2427-06-7
• Molecular Formula: C10H14N2
• Molecular Weight: 162.2316
• Mol file: 2427-06-7.mol

Synonyms:

Chemical Property of 1,4-dimethyl-1,2,3,4-tetrahydroquinoxaline

Chemical Property:

• Vapor Pressure: 0.011mmHg at 25°C
• Boiling Point: 262.3°Cat760mmHg
• Flash Point: 106.8°C
• Density: 1.024g/cm³

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1,4-dimethyl-1,2,3,4-tetrahydroquinoxaline

There total 13 articles about 1,4-dimethyl-1,2,3,4-tetrahydroquinoxaline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

2,3-diethynylquinoxaline (91-19-0) + formic acid (64-18-6) → 1,4-dimethyl-1,2,3,4-tetrahydroquinoxaline (2427-06-7)

Guidance literature:

With C₂₀H₂₅IrN₂O₃; at 50 ℃; for 20h;

DOI:10.1002/cctc.202101099

Reference yield: 78.0%

1,2-Diiodobenzene (615-42-9) + N,N`-dimethylethylenediamine (110-70-3) → 1,4-dimethyl-1,2,3,4-tetrahydroquinoxaline (2427-06-7)

Guidance literature:

With copper(l) iodide; 1,8-diazabicyclo[5.4.0]undec-7-ene; at 110 ℃; for 24h; Reagent/catalyst; Temperature; Catalytic behavior; Schlenk technique; Inert atmosphere;

DOI:10.1055/s-0036-1588145

Reference yield: 60.0%

1,2-dimethoxybenzene (91-16-7) + N,N`-dimethylethylenediamine (110-70-3) → 1,4-dimethyl-1,2,3,4-tetrahydroquinoxaline (2427-06-7)

Guidance literature:

With n-butyllithium; In tetrahydrofuran; hexane; 1.) 0 deg C, 30 min; room temp., 1 h, 2.) reflux, overnight;

DOI:10.1021/jo00071a019

upstream raw materials:

1,4-diformyl-1,2,3,4-tetrahydroquinoxaline

N-(3-chloro-phenyl)-N,N'-dimethyl-ethylenediamine

1,2-dimethoxybenzene

N,N`-dimethylethylenediamine