1,1'-Biphenyl, 4-phenoxy-

Base Information

• Chemical Name: 1,1'-Biphenyl, 4-phenoxy-
• CAS No.: 3933-94-6
• Molecular Formula: C18H14 O
• Molecular Weight: 246.309
• Hs Code.: 2909309090
• European Community (EC) Number: 223-504-4
• NSC Number: 66281
• UNII: T8UU6VJF7V
• DSSTox Substance ID: DTXSID8073970
• Nikkaji Number: J102.861H
• Wikidata: Q82002524
• Mol file: 3933-94-6.mol

Synonyms:4-Phenoxybiphenyl;3933-94-6;1,1'-Biphenyl, 4-phenoxy-;1-phenoxy-4-phenylbenzene;4-Phenoxy-1,1'-biphenyl;Ether, 4-biphenylyl phenyl;4-Biphenylyl phenyl ether;p-Diphenyl phenyl ether;Phenoxy-4-diphenyl;T8UU6VJF7V;EINECS 223-504-4;NSC-66281;AI3-01013;4-Phenyloxybiphenyl;p-phenoxybiphenyl;4-phenoxy biphenyl;1, 4-phenoxy-;UNII-T8UU6VJF7V;SCHEMBL403667;4-Phenoxy-1,1'-biphenyl #;4-BiphenylylphenylA currencyther;DTXSID8073970;NSC66281;MFCD00016573;NSC 66281;AKOS024323115;CS-0452042;FT-0755211

Chemical Property of 1,1'-Biphenyl, 4-phenoxy-

Chemical Property:

• Boiling Point: 374.8°Cat760mmHg
• Flash Point: 178.2°C
• PSA: 9.23000
• Density: 1.093g/cm³
• LogP: 5.14590
• XLogP3: 5.5
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 3
• Exact Mass: 246.104465066
• Heavy Atom Count: 19
• Complexity: 242

Purity/Quality:

98%min ^*data from raw suppliers

4-Phenoxybiphenyl ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C2=CC=C(C=C2)OC3=CC=CC=C3

Technology Process of 1,1'-Biphenyl, 4-phenoxy-

There total 38 articles about 1,1'-Biphenyl, 4-phenoxy- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

iodobenzene (591-50-4) + 4-Phenylphenol (92-69-3) → 4-Phenoxybiphenyl (3933-94-6)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; at 110 ℃;

DOI:10.1055/s-0028-1083304

Reference yield: 99.0%

4-Phenylphenol (92-69-3) + chlorobenzene (108-90-7) → 4-Phenoxybiphenyl (3933-94-6)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; at 110 ℃; for 12h;

DOI:10.1002/adsc.201000977

Reference yield: 96.0%

4-bromo-1,1'-biphenyl (92-66-0) + phenol (108-95-2,27073-41-2) → 4-Phenoxybiphenyl (3933-94-6)

Guidance literature:

With potassium phosphate; copper(l) iodide; N,N’-bis(2-phenylphenyl)oxalic acid; In acetonitrile; at 90 ℃; for 24h; Solvent; Schlenk technique; Inert atmosphere; Sealed tube;

DOI:10.1021/acs.joc.7b00493

upstream raw materials:

4-Phenylphenol

chlorobenzene

4-bromo-1,1'-biphenyl

phenol

Downstream raw materials:

4-Phenylphenol

phenol

3-(4-p-Diphenyloxybenzoyl)propionsaeure

1-p-Acetylphenyl-4-p-acetylphenoxybenzol

Refernces

• 1、 Chen, Yuning,Feng, Li. "Silver nanoparticles doped TiO2 catalyzed Suzuki-coupling of bromoaryl with phenylboronic acid under visible light". . . Retrieved 2020.
• 2、 Zhu, Da-Liang,Jiang, Shan,Wu, Qi,Wang, Hao,Li, Hai-Yan,Li, Hong-Xi. "Nickel-Catalyzed Etherification of Phenols and Aryl Halides through Visible-Light-Induced Energy Transfer". supporting information. p. 8327 - 8332. Retrieved 2021/10/25.
• 3、 Eslahi, Hassan,Sardarian, Ali Reza,Esmaeilpour, Mohsen. "Green and sustainable palladium nanomagnetic catalyst stabilized by glucosamine-functionalized Fe3O4@SiO2 nanoparticles for Suzuki and Heck reactions". . . Retrieved 2021/04/26.