Sophoraflavanone G

Base Information

• Chemical Name: Sophoraflavanone G
• CAS No.: 97938-30-2
• Deprecated CAS: 34981-24-3,36545-61-6,99211-14-0,124858-43-1,352220-39-4
• Molecular Formula: C₂₅H₂₈O₆
• Molecular Weight: 424.494
• DSSTox Substance ID: DTXSID10243345
• Nikkaji Number: J343.459A
• Wikipedia: Sophoraflavanone_G
• Wikidata: Q7563137
• Pharos Ligand ID: V6JWGX8P4QPK
• Metabolomics Workbench ID: 57370
• ChEMBL ID: CHEMBL243148
• Mol file: 97938-30-2.mol

Synonyms:5,7,2',4'-tetrahydroxy-8-lavandulyl-flavanone;sophoraflavanone G;vexibinol

Chemical Property of Sophoraflavanone G

Chemical Property:

• Vapor Pressure: 1.55E-18mmHg at 25°C
• Melting Point: 173-175℃
• Boiling Point: 659.3°Cat760mmHg
• PKA: 7.66±0.40(Predicted)
• Flash Point: 224.8°C
• PSA: 107.22000
• Density: 1.266g/cm³
• LogP: 5.30660
• XLogP3: 5.8
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 6
• Exact Mass: 424.18858861
• Heavy Atom Count: 31
• Complexity: 684

Purity/Quality:

98%Min ^*data from raw suppliers

SophoraflavanoneG ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(=CCC(CC1=C2C(=C(C=C1O)O)C(=O)CC(O2)C3=C(C=C(C=C3)O)O)C(=C)C)C
• Isomeric SMILES: CC(=CC[C@H](CC1=C2C(=C(C=C1O)O)C(=O)C[C@H](O2)C3=C(C=C(C=C3)O)O)C(=C)C)C
• Uses: Sophoraflavanone G is a flavonoids of Sophora flavescens Ait. which exhibits antibacterial activity. Also, it is reported to exhibits anti-inflammatory activity.

Technology Process of Sophoraflavanone G

There total 1 articles about Sophoraflavanone G which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

dimethylallyl diphosphate (780724-90-5) + (2S)-2-(2,4-dihydroxyphenyl)-2,3-dihydro-5,7-dihydroxy-4H-1-benzopyran-4-one (56486-94-3) → sophoraflavone G (1049662-29-4,97938-30-2) + 8-dimethylallylsteppogenin (152464-78-3) + 6-dimethylallyl-2'-hydroxynaringenin (597542-74-0)

Guidance literature:

With naringenin 8-dimethylallyltransferase; magnesium chloride; In ethanol; water; at 25 ℃; pH=7.5 - 9; Enzymatic reaction;

DOI:10.1016/S0031-9422(00)00198-9

upstream raw materials:

dimethylallyl diphosphate

(2S)-2-(2,4-dihydroxyphenyl)-2,3-dihydro-5,7-dihydroxy-4H-1-benzopyran-4-one

Refernces