Technology Process of 4-Pentenal, 2,2-dimethyl-3-(phenylmethoxy)-, (3S)-
There total 6 articles about 4-Pentenal, 2,2-dimethyl-3-(phenylmethoxy)-, (3S)- which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
pyridinium chlorochromate;
In
dichloromethane;
at 20 ℃;
for 8h;
Inert atmosphere;
DOI:10.1021/jo102401v
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: 484 mg / DIBAL / toluene / 2 h / -78 °C
2.1: BuLi / hexane; tetrahydrofuran
2.2: 323 mg / tetrahydrofuran; hexane / 3 h / 0 °C
3.1: 310 mg / oxalyl chloride; DMSO; Et3N / CH2Cl2 / -78 - 20 °C
With
n-butyllithium; oxalyl dichloride; diisobutylaluminium hydride; dimethyl sulfoxide; triethylamine;
In
tetrahydrofuran; hexane; dichloromethane; toluene;
2.2: Wittig reaction / 3.1: Swern oxidation;
DOI:10.1016/S0040-4020(03)00297-7
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: BuLi / hexane; tetrahydrofuran
1.2: 323 mg / tetrahydrofuran; hexane / 3 h / 0 °C
2.1: 310 mg / oxalyl chloride; DMSO; Et3N / CH2Cl2 / -78 - 20 °C
With
n-butyllithium; oxalyl dichloride; dimethyl sulfoxide; triethylamine;
In
tetrahydrofuran; hexane; dichloromethane;
1.2: Wittig reaction / 2.1: Swern oxidation;
DOI:10.1016/S0040-4020(03)00297-7
