6-Benzyl-4-chloro-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidin-2-amine

Base Information

Chemical Name:6-Benzyl-4-chloro-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidin-2-amine
CAS No.:570415-48-4
Molecular Formula:C14H15ClN4
Molecular Weight:274.753
Hs Code.:2933990090
DSSTox Substance ID:DTXSID70559777
Wikidata:Q82442620

Synonyms:6-Benzyl-4-chloro-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidin-2-amine;570415-48-4;SCHEMBL116582;DTXSID70559777;AIFHNRTXIAZQOR-UHFFFAOYSA-N;6-benzyl-4-chloro-7,8-dihydro-5H-pyrido[4,3-d]pyrimidin-2-amine;6-benzyl-4-chloro-5,6,7,8-tetrahydro-pyrido[4,3-d]pyrimidin-2-ylamine

Suppliers and Price of 6-Benzyl-4-chloro-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidin-2-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
6-Benzyl-4-chloro-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidin-2-amine 95+%
1g
$ 772.00

American Custom Chemicals Corporation
6-BENZYL-4-CHLORO-5,6,7,8-TETRAHYDROPYRIDO[4,3-D]PYRIMIDIN-2-AMINE 95.00%
5MG
$ 505.12

Alichem
6-Benzyl-4-chloro-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidin-2-amine
1g
$ 634.28

Total 3 raw suppliers

Chemical Property of 6-Benzyl-4-chloro-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidin-2-amine

Chemical Property:

PSA：55.77000
LogP:2.13850
Storage Temp.:2-8°C
XLogP3:2.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:274.0985242
Heavy Atom Count:19
Complexity:295

Purity/Quality:

98%Min ^*data from raw suppliers

6-Benzyl-4-chloro-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidin-2-amine 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1CN(CC2=C1N=C(N=C2Cl)N)CC3=CC=CC=C3

Technology Process of 6-Benzyl-4-chloro-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidin-2-amine

There total 3 articles about 6-Benzyl-4-chloro-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidin-2-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 57.0%

: 1029-52-3
2-amino-6-benzyl-5,6,7,8-tetrahydropyrido<4,3-d>pyrimidin-4(3H)-one

: 570415-48-4
6-benzyl-4-chloro-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidin-2-amine

Guidance literature:: 2-amino-6-benzyl-5,6,7,8-tetrahydropyrido<4,3-d>pyrimidin-4(3H)-one; With trichlorophosphate; In N,N-dimethyl-formamide; at 110 ℃; Inert atmosphere;

With ammonia; In N,N-dimethyl-formamide; pH=4; Cooling with ice;

Reference yield:

: 62458-92-8
2-amino-7-benzyl-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-4(4aH)-one

: 570415-48-4
6-benzyl-4-chloro-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidin-2-amine

Guidance literature:: With trichlorophosphate; for 5h; Heating / reflux;

Reference yield:

: 1454-53-1
ethyl 1-benzyl-4-oxopiperidine-3-carboxylate hydrochloride

: 570415-48-4
6-benzyl-4-chloro-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidin-2-amine

Guidance literature:: Multi-step reaction with 2 steps

1: ethanol / 16 h / 120 °C

2: trichlorophosphate / 16 h / 100 °C

With trichlorophosphate; In ethanol;