17,19,21-Trihydroxypregn-4-ene-3,20-dione

Base Information

Chemical Name:17,19,21-Trihydroxypregn-4-ene-3,20-dione
CAS No.:510-65-6
Molecular Formula:C21H30O5
Molecular Weight:362.466
Hs Code.:
UNII:WR99YG9GNV
DSSTox Substance ID:DTXSID20965283
Nikkaji Number:J67.002B
Wikidata:Q82947474
Mol file:510-65-6.mol

Synonyms:17,19,21-Trihydroxypregn-4-ene-3,20-dione;510-65-6;BRN 3172504;17,19,21-Trihydroxyprogesterone;WR99YG9GNV;Pregn-4-ene-3,20-dione, 17,19,21-trihydroxy-;4-Pregnene-17alpha,19,21-triol-3,20-dione;4-08-00-03434 (Beilstein Handbook Reference);UNII-WR99YG9GNV;(8R,9S,10S,13S,14S,17R)-17-hydroxy-17-(2-hydroxyacetyl)-10-(hydroxymethyl)-13-methyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one;19-Hydroxy-11-deoxycortisol;DTXSID20965283;4-Pregnen-17,19,21-triol-3,20-dione;LS-118728

Suppliers and Price of 17,19,21-Trihydroxypregn-4-ene-3,20-dione

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
19-HYDROXY SUBSTANCE S 98.00%
100MG
$ 1963.50

Total 6 raw suppliers

Chemical Property of 17,19,21-Trihydroxypregn-4-ene-3,20-dione

Chemical Property:

Vapor Pressure:1.12E-15mmHg at 25°C
Boiling Point:576.3°Cat760mmHg
Flash Point:316.3°C
PSA：94.83000
Density:1.29g/cm³
LogP:1.78320
XLogP3:1.3
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:3
Exact Mass:362.20932405
Heavy Atom Count:26
Complexity:669

Purity/Quality:

98%min ^*data from raw suppliers

19-HYDROXY SUBSTANCE S 98.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC12CCC3C(C1CCC2(C(=O)CO)O)CCC4=CC(=O)CCC34CO
Isomeric SMILES:C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@@]2(C(=O)CO)O)CCC4=CC(=O)CC[C@]34CO

Technology Process of 17,19,21-Trihydroxypregn-4-ene-3,20-dione

There total 4 articles about 17,19,21-Trihydroxypregn-4-ene-3,20-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 152-58-9
Cortexolone

: 50-23-7
HYDROCORTISONE

: 510-65-6
19-hydroxycortodoxone

Guidance literature:: With water; iron(II) sulfate; In N,N-dimethyl-formamide; at 30 ℃; for 72h; Reagent/catalyst; Enzymatic reaction;
DOI:10.1038/s41467-019-11344-0

Reference yield:

: 19357-45-0
17α,21-dihydroxy-4-pregnene-3,20-dione 17-acetate

: 50-23-7
HYDROCORTISONE

: 510-65-6
19-hydroxycortodoxone

Guidance literature:: With water; iron(II) sulfate; In N,N-dimethyl-formamide; at 30 ℃; for 72h; Enzymatic reaction;
DOI:10.1038/s41467-019-11344-0

Reference yield:

: 640-87-9
cortexolone 21-acetate

: 50-23-7
HYDROCORTISONE

: 510-65-6
19-hydroxycortodoxone

Guidance literature:: With water; iron(II) sulfate; In N,N-dimethyl-formamide; at 30 ℃; for 72h; Enzymatic reaction;
DOI:10.1038/s41467-019-11344-0