Pyrazolidine-3,5-dione

Base Information

Chemical Name:Pyrazolidine-3,5-dione
CAS No.:4744-71-2
Molecular Formula:C3H4N2O2
Molecular Weight:100.077
Hs Code.:
European Community (EC) Number:826-090-9
DSSTox Substance ID:DTXSID101346761
Nikkaji Number:J274.753G
Mol file:4744-71-2.mol

Synonyms:pyrazolidine-3,5-dione

Suppliers and Price of Pyrazolidine-3,5-dione

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
3,5-PYRAZOLIDINEDIONE 95.00%
5MG
$ 503.97

Total 7 raw suppliers

Chemical Property of Pyrazolidine-3,5-dione

Chemical Property:

Melting Point:290 °C (decomp)(Solv: methanol (67-56-1))
PKA:8.62±0.20(Predicted)
PSA：58.20000
Density:1.356±0.06 g/cm3(Predicted)
LogP:-0.80490
XLogP3:-1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:100.027277375
Heavy Atom Count:7
Complexity:106

Purity/Quality:

99%, ^*data from raw suppliers

3,5-PYRAZOLIDINEDIONE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1C(=O)NNC1=O

Technology Process of Pyrazolidine-3,5-dione

There total 5 articles about Pyrazolidine-3,5-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

: 30866-24-1
ethyl 3-hydrazino-3-oxopropanoate

: 4744-71-2
pyrazolidine‐3,5‐dione

Guidance literature:: With sodium methylate; In methanol; for 24h;
DOI:10.1002/ardp.19863190114

Reference yield: 41.0%

: 3815-86-9
malonic acid dihydrazide

: 56043-02-8
N-Phenyl-trithioisatosaeureanhydrid

: 4744-71-2
pyrazolidine‐3,5‐dione

: 83388-69-6
2,5-Bis(2-phenylamino-phenyl)-1,3,4-thiadiazol

Guidance literature:: In various solvent(s); for 0.5h; Heating;
DOI:10.1007/BF00799952

Reference yield: 38.2%

: 105-53-3
diethyl malonate

: 4744-71-2
pyrazolidine‐3,5‐dione

Guidance literature:: diethyl malonate; With hydrazine hydrate; In ethanol; at 20 ℃; for 5h;

With sodium methylate; In methanol; for 8h; Reflux;

With hydrogenchloride; In water; at 4 ℃; pH=2 - 3;
DOI:10.1039/c9nj00574a