Benzo[f]quinazoline, 1,3-diphenyl-

Base Information

• Chemical Name: Benzo[f]quinazoline, 1,3-diphenyl-
• CAS No.: 60708-99-8
• Molecular Formula: C24H16N2
• Molecular Weight: 332.404
• DSSTox Substance ID: DTXSID70484515
• Nikkaji Number: J2.287.010F
• Wikidata: Q82322952
• Mol file: 60708-99-8.mol

Synonyms:Benzo[f]quinazoline, 1,3-diphenyl-;60708-99-8;SCHEMBL25931444;DTXSID70484515

Chemical Property of Benzo[f]quinazoline, 1,3-diphenyl-

Chemical Property:

• XLogP3: 6.1
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 332.131348519
• Heavy Atom Count: 26
• Complexity: 451

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C2=NC(=NC3=C2C4=CC=CC=C4C=C3)C5=CC=CC=C5

Technology Process of Benzo[f]quinazoline, 1,3-diphenyl-

There total 5 articles about Benzo[f]quinazoline, 1,3-diphenyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

1,3-diphenyl-5,6-dihydrobenzo[f]quinazoline → 1,3-diphenylbenzo[f]quinazoline (60708-99-8)

Guidance literature:

With 2,3-dicyano-5,6-dichloro-p-benzoquinone; In 1,2-dichloro-benzene; at 120 ℃; for 3h;

DOI:10.1016/j.tet.2006.01.010

Reference yield: 78.0%

benzaldehyde (100-52-7) + naphthalen-2-ylamine (91-59-8) → 1,3-diphenylbenzo[f]quinazoline (60708-99-8)

Guidance literature:

With ammonium iodide; oxygen; dimethyl sulfoxide; In chlorobenzene; at 150 ℃; for 12h;

DOI:10.1039/c8gc02654h

Reference yield:

benzonitrile (100-47-0) + naphthalen-2-ylamine (91-59-8) → 1,3-diphenylbenzo[f]quinazoline (60708-99-8)

Guidance literature:

naphthalen-2-ylamine; With tetrafluoroboric acid; sodium nitrite; In water; at 0 ℃; for 0.5h;

benzonitrile; at 110 ℃; for 3h; Sealed tube;

DOI:10.1021/acs.joc.7b01325

upstream raw materials:

N-(2-naphthyl)benzimidoyl chloride

benzonitrile

naphthalen-2-ylamine

benzaldehyde