1-(2,4-Dimethoxyphenyl)-2,2-dimethylpropan-1-one

Base Information

Chemical Name:1-(2,4-Dimethoxyphenyl)-2,2-dimethylpropan-1-one
CAS No.:60884-08-4
Molecular Formula:C13H18O3
Molecular Weight:222.284
Hs Code.:
DSSTox Substance ID:DTXSID00489119
Nikkaji Number:J2.034.972G
Wikidata:Q82332216

Synonyms:1-(2,4-Dimethoxyphenyl)-2,2-dimethylpropan-1-one;60884-08-4;SCHEMBL855232;DTXSID00489119;AKOS012098046;1-(2,4-dimethoxyphenyl)-2,2-dimethyl-1-propanone;1-(2,4-Dimethoxy-phenyl)-2,2-dimethyl-propan-1-one

Suppliers and Price of 1-(2,4-Dimethoxyphenyl)-2,2-dimethylpropan-1-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of 1-(2,4-Dimethoxyphenyl)-2,2-dimethylpropan-1-one

Chemical Property:

PSA：35.53000
LogP:2.93260
XLogP3:2.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:222.125594432
Heavy Atom Count:16
Complexity:242

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)C(=O)C1=C(C=C(C=C1)OC)OC

Technology Process of 1-(2,4-Dimethoxyphenyl)-2,2-dimethylpropan-1-one

There total 9 articles about 1-(2,4-Dimethoxyphenyl)-2,2-dimethylpropan-1-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 3282-30-2
pivaloyl chloride

: 151-10-0
1,3-Dimethoxybenzene

: 60884-08-4
1-(2,4-dimethoxyphenyl)-2,2-dimethylpropan-1-one

Guidance literature:: With indium(III) tosylate; In nitromethane; for 2h; Reflux;
DOI:10.1016/j.tet.2015.07.027

Reference yield:

: 39828-35-8
2,4-dimethoxybenzoyl chloride

: 594-19-4
tert.-butyl lithium

: 60884-08-4
1-(2,4-dimethoxyphenyl)-2,2-dimethylpropan-1-one

Guidance literature:: tert.-butyl lithium; With copper(I) bromide dimethylsulfide complex; In tetrahydrofuran; at -78 ℃; for 0.5h;

2,4-dimethoxybenzoyl chloride; In tetrahydrofuran; at -78 - 20 ℃; for 6h;
DOI:10.1016/j.tetlet.2019.151394

Reference yield:

: 111122-89-5
2-tert-Butyl-2-(2,4-dimethoxy-phenyl)-benzo[1,3]oxathiole

: 60884-08-4
1-(2,4-dimethoxyphenyl)-2,2-dimethylpropan-1-one

Guidance literature:: With tetrafluoroboric acid; mercury(II) oxide; In tetrahydrofuran; Yield given; Ambient temperature;
DOI:10.1055/s-1987-27931