2(1H)-Isoquinolinemethanamine, 3,4-dihydro-N-(4-chlorophenyl)-6,7-dimethoxy-1-(1H-indol-3-ylmethyl)-

Base Information

Chemical Name:2(1H)-Isoquinolinemethanamine, 3,4-dihydro-N-(4-chlorophenyl)-6,7-dimethoxy-1-(1H-indol-3-ylmethyl)-
CAS No.:84218-39-3
Molecular Formula:C₂₇H₂₈ClN₃O₂
Molecular Weight:461.991
Hs Code.:
DSSTox Substance ID:DTXSID501004478
Mol file:84218-39-3.mol

Synonyms:84218-39-3;2(1H)-Isoquinolinemethanamine, 3,4-dihydro-N-(4-chlorophenyl)-6,7-dimethoxy-1-(1H-indol-3-ylmethyl)-;2(1H)-Isoquinolinemethanamine,3,4-dihydro-N-(4-chlorophenyl)-6,7-dimethoxy-1-(1H-indol-3-ylmethyl)-;DTXSID501004478;LS-85717;4-Chloro-N-({1-[(1H-indol-3-yl)methyl]-6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl}methyl)aniline

Suppliers and Price of 2(1H)-Isoquinolinemethanamine, 3,4-dihydro-N-(4-chlorophenyl)-6,7-dimethoxy-1-(1H-indol-3-ylmethyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
2(1H)-ISOQUINOLINEMETHANAMINE, 3,4-DIHYDRO-N-(4-CHLOROPHENYL)-6,7-DIME THOXY-1-(1H-INDOL-3-YLMETHYL)- 95.00%
5MG
$ 501.46

Total 0 raw suppliers

Chemical Property of 2(1H)-Isoquinolinemethanamine, 3,4-dihydro-N-(4-chlorophenyl)-6,7-dimethoxy-1-(1H-indol-3-ylmethyl)-

Chemical Property:

Vapor Pressure:7.78E-18mmHg at 25°C
Boiling Point:670.4°C at 760 mmHg
Flash Point:359.2°C
PSA：49.52000
Density:1.272g/cm³
LogP:6.06090
XLogP3:6.3
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:7
Exact Mass:461.1870048
Heavy Atom Count:33
Complexity:616

Purity/Quality:: 2(1H)-ISOQUINOLINEMETHANAMINE, 3,4-DIHYDRO-N-(4-CHLOROPHENYL)-6,7-DIME THOXY-1-(1H-INDOL-3-YLMETHYL)- 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=C(C=C2C(N(CCC2=C1)CNC3=CC=C(C=C3)Cl)CC4=CNC5=CC=CC=C54)OC

Technology Process of 2(1H)-Isoquinolinemethanamine, 3,4-dihydro-N-(4-chlorophenyl)-6,7-dimethoxy-1-(1H-indol-3-ylmethyl)-

There total 4 articles about 2(1H)-Isoquinolinemethanamine, 3,4-dihydro-N-(4-chlorophenyl)-6,7-dimethoxy-1-(1H-indol-3-ylmethyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 67.0%

: 50-00-0,30525-89-4,61233-19-0
formaldehyd

: 106-47-8
4-chloro-aniline

: 15832-21-0
1-((1H-indol-3-yl)methyl)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline

: 84218-39-3
6,7-dimethoxy-1-(indolyl-3-methyl)-2-(4-chlorphenyl-aminomethyl)-1,2,3,4-tetrahydroisoquinoline

Guidance literature:

Reference yield:

: 87-51-4
indole-3-acetic acid

: 84218-39-3
6,7-dimethoxy-1-(indolyl-3-methyl)-2-(4-chlorphenyl-aminomethyl)-1,2,3,4-tetrahydroisoquinoline

Guidance literature:: Multi-step reaction with 3 steps

1: 80 percent / 3 h / 170 °C

2: 90 percent / POCl₃ / CHCl₃ / 3 h / Heating

3: 67 percent

With trichlorophosphate; In chloroform;

Reference yield:

: 120-20-7
2-(3,4-dimethoxyphenyl)-ethylamine

: 84218-39-3
6,7-dimethoxy-1-(indolyl-3-methyl)-2-(4-chlorphenyl-aminomethyl)-1,2,3,4-tetrahydroisoquinoline

Guidance literature:: Multi-step reaction with 3 steps

1: 80 percent / 3 h / 170 °C

2: 90 percent / POCl₃ / CHCl₃ / 3 h / Heating

3: 67 percent

With trichlorophosphate; In chloroform;