2-(4-methoxyphenyl)-3-phenyl-2,3-dihydroquinazolin-4(1H)-one

Base Information

Chemical Name:2-(4-methoxyphenyl)-3-phenyl-2,3-dihydroquinazolin-4(1H)-one
CAS No.:63384-41-8
Molecular Formula:C21H18N2O2
Molecular Weight:330.386
Hs Code.:
DSSTox Substance ID:DTXSID50386129
Nikkaji Number:J2.879.151H
ChEMBL ID:CHEMBL2322647
Mol file:63384-41-8.mol

Synonyms:2-(4-methoxyphenyl)-3-phenyl-2,3-dihydroquinazolin-4(1H)-one;63384-41-8;ChemDiv3_000950;Oprea1_604526;Oprea1_756001;CHEMBL2322647;SCHEMBL15641850;DTXSID50386129;HMS1475L04;STK020655;AKOS000616894;AKOS021986742;WAY-297749;IDI1_019916;AB00089676-01;AG-205/36483053;SR-01000407829;SR-01000407829-1;2-(4-methoxyphenyl)-3-phenyl-1,2,3,4-tetrahydroquinazolin-4-one;2-(4-Methoxyphenyl)-3-phenyl-1,2-dihydroquinazoline-4(3H)-one

Suppliers and Price of 2-(4-methoxyphenyl)-3-phenyl-2,3-dihydroquinazolin-4(1H)-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 2-(4-methoxyphenyl)-3-phenyl-2,3-dihydroquinazolin-4(1H)-one

Chemical Property:

PSA：41.57000
LogP:4.66930
XLogP3:4.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:330.136827821
Heavy Atom Count:25
Complexity:455

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC=C(C=C1)C2NC3=CC=CC=C3C(=O)N2C4=CC=CC=C4

Technology Process of 2-(4-methoxyphenyl)-3-phenyl-2,3-dihydroquinazolin-4(1H)-one

There total 11 articles about 2-(4-methoxyphenyl)-3-phenyl-2,3-dihydroquinazolin-4(1H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 123-11-5
4-methoxy-benzaldehyde

: 4424-17-3
2-aminobenzanilide

: 63384-41-8
2-(4-methoxyphenyl)-3-phenyl-2,3-dihydroquinazolin-4(1H)-one

Guidance literature:: With indium(III) bromide; In acetonitrile; at 20 ℃; for 0.166667h;
DOI:10.1080/00397911.2015.1046555

Reference yield: 95.0%

: 118-48-9
isatoic anhydride

: 123-11-5
4-methoxy-benzaldehyde

: 62-53-3
aniline

: 63384-41-8
2-(4-methoxyphenyl)-3-phenyl-2,3-dihydroquinazolin-4(1H)-one

Guidance literature:: With strontium (III) chloride hexahydrate; In ethanol; water; for 1.5h; Reflux;
DOI:10.1016/j.cclet.2011.06.002

Reference yield: 91.0%

: 118-48-9
isatoic anhydride

: 62-53-3
aniline

: 105-13-5
4-Methoxybenzyl alcohol

: 63384-41-8
2-(4-methoxyphenyl)-3-phenyl-2,3-dihydroquinazolin-4(1H)-one

Guidance literature:: isatoic anhydride; aniline; In dimethyl sulfoxide; at 80 ℃; for 0.333333h;

4-Methoxybenzyl alcohol; With hydrogen bromide; In dimethyl sulfoxide; at 80 ℃; for 0.166667h;
DOI:10.1055/s-0036-1591544