2-Amino-6-(methylsulfonyl)benzothiazole

Base Information

Chemical Name:2-Amino-6-(methylsulfonyl)benzothiazole
CAS No.:17557-67-4
Molecular Formula:C8H8N2O2S2
Molecular Weight:228.296
Hs Code.:2934999090
European Community (EC) Number:241-537-2
DSSTox Substance ID:DTXSID4051796
Nikkaji Number:J37.328A
Wikidata:Q72439676
ChEMBL ID:CHEMBL432942
Mol file:17557-67-4.mol

Synonyms:17557-67-4;2-Amino-6-(methylsulfonyl)benzothiazole;6-(methylsulfonyl)-1,3-benzothiazol-2-amine;2-Amino-6-methylsulfonylbenzothiazole;2-Benzothiazolamine, 6-(methylsulfonyl)-;6-methylsulfonyl-1,3-benzothiazol-2-amine;6-methanesulfonyl-1,3-benzothiazol-2-amine;2-Aminobenzothiazole-6-methyl sulfone;6-(Methylsulfonyl)-2-benzothiazolamine;6-(methylsulfonyl)benzo[d]thiazol-2-amine;EINECS 241-537-2;2-Aminobenzothiazolyl-6 methyl sulfone;6-Methylsulphonylbenzothiazol-2-ylamine;CHEMBL432942;6-Methanesulfonyl-benzothiazol-2-ylamine;2-Amino-6-[methylsulfonyl]benzothiazole;6-(Methylsulfonyl)benzothiazole-2-ylamine;Maybridge1_008993;MixCom3_000185;2-amino-6-(methylsulfonyl);Oprea1_366974;MLS000084909;BIDD:GT0409;SCHEMBL686784;DTXSID4051796;HMS2357K17;6-methylsulfonyl-2-aminobenzothiazole;AC-062;BDBM50335097;CCG-52088;MFCD00179133;STK374502;6-Methylsulfonyl)-2-benzothiazolamine;2-amino-6-methanesulfonylbenzothiazole;AKOS000119152;2-Amino-6-(methylsulfonyl)benzothiazol;6-(methylsulfonyl)benzothiazol-2-amine;6-Methanesulphonyl-2-aminobenzothiazole;CS-W010405;FS-3036;SDCCGMLS-0054993.P002;2-amino-6-methanesulfonyl-benzothiazole;LS-40631;SMR000019255;AM20030165;FT-0611193;EN300-21444;6-(methylsulfonyl)-1,3-benzothiazol-2-ylamine;SR-01000616101-2;W-107846;6-(Methylsulfonyl)-1,3-benzothiazol-2(3H)-imine #;BRD-K50180361-001-08-0;F0901-0841;Z203045054;EUE

Suppliers and Price of 2-Amino-6-(methylsulfonyl)benzothiazole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-Amino-6-(methylsulfonyl)benzothiazole
5g
$ 60.00

Oakwood
6-(Methylsulfonyl)-1,3-benzothiazol-2-amine 97%
1g
$ 10.00

Matrix Scientific
6-(Methylsulfonyl)-1,3-benzothiazol-2-amine 95+%
10g
$ 155.00

Matrix Scientific
6-(Methylsulfonyl)-1,3-benzothiazol-2-amine 95+%
1g
$ 30.00

Matrix Scientific
6-(Methylsulfonyl)-1,3-benzothiazol-2-amine 95+%
5g
$ 90.00

Crysdot
6-(Methylsulfonyl)-1,3-benzothiazol-2-amine 97%
25g
$ 89.00

Chemcia Scientific
6-Methanesulfonyl-benzothiazol-2-ylamine ＞95%
25 G
$ 150.00

Total 68 raw suppliers

Chemical Property of 2-Amino-6-(methylsulfonyl)benzothiazole

Chemical Property:

Appearance/Colour:white to light yellow powder
Vapor Pressure:3.68E-10mmHg at 25°C
Melting Point:223 °C (dec.)(lit.)
Refractive Index:1.687
Boiling Point:500.8 °C at 760 mmHg
PKA:1.99±0.10(Predicted)
Flash Point:256.7 °C
PSA：109.67000
Density:1.518 g/cm³
LogP:2.94400
XLogP3:1.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:1
Exact Mass:228.00271985
Heavy Atom Count:14
Complexity:312

Purity/Quality:

99% ^*data from raw suppliers

2-Amino-6-(methylsulfonyl)benzothiazole ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi, Xn
Hazard Codes:Xi,Xn
Statements: 36/37/38-22
Safety Statements: 26-36-36/37/39-22

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CS(=O)(=O)C1=CC2=C(C=C1)N=C(S2)N
Uses 2-Amino-6-(Methylsulfonyl)benzothiazole is used in preparation of benzothiazole carboxamides as RIG-1 agonists for treatment cell proliferation disorders.

Technology Process of 2-Amino-6-(methylsulfonyl)benzothiazole

There total 12 articles about 2-Amino-6-(methylsulfonyl)benzothiazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

: 5470-49-5
4-methanesulfonylphenylamine

: 1147550-11-5
ammonium thiocyanate

: 17557-67-4
2-amino-6-(methylsulfonyl)benzothiazole

Guidance literature:: With tris(2,2'-bipyridyl)ruthenium dichloride; In acetonitrile; at 20 ℃; for 18h; Irradiation;
DOI:10.1016/j.tetlet.2020.151700

Reference yield: 75.0%

: 5470-49-5
4-methanesulfonylphenylamine

: 333-20-0
potassium thioacyanate

: 17557-67-4
2-amino-6-(methylsulfonyl)benzothiazole

Guidance literature:: 4-methanesulfonylphenylamine; potassium thioacyanate; With acetic acid; at 20 ℃; for 1h;

With bromine; at 0 - 20 ℃; for 6h;
DOI:10.1039/d0ra00663g