2-[2-(2-Methoxyethoxy)ethoxy]-2-methylpropane

Base Information

• Chemical Name: 2-[2-(2-Methoxyethoxy)ethoxy]-2-methylpropane
• CAS No.: 52788-79-1
• Molecular Formula: C₉H₂₀O₃
• Molecular Weight: 176.256
• European Community (EC) Number: 258-182-4
• UNII: DK8RLU6FNJ
• DSSTox Substance ID: DTXSID6068804
• Nikkaji Number: J236.452B
• Wikidata: Q81995573
• Mol file: 52788-79-1.mol

Synonyms:52788-79-1;2-[2-(2-Methoxyethoxy)ethoxy]-2-methylpropane;2-(2-(2-Methoxyethoxy)ethoxy)-2-methylpropane;Propane, 2-[2-(2-methoxyethoxy)ethoxy]-2-methyl-;DK8RLU6FNJ;DIETHYLENEGLYCOL METHYL-TERT-BUTYL ETHE&;EINECS 258-182-4;Propane, 2-(2-(2-methoxyethoxy)ethoxy)-2-methyl-;Diethylene glycol methyl tert-butyl ether;Diethylene glycol tert-butyl methyl ether;Diethyleneglycoltert-butylmethyletherTech.;UNII-DK8RLU6FNJ;Diethylene glycol tert-butyl ether methyl ether;SCHEMBL2822049;DTXSID6068804;IVBLRSMVJDVLCP-UHFFFAOYSA-;MFCD00008814;Diethylene glycol methyl-tert-butyl ether

Chemical Property of 2-[2-(2-Methoxyethoxy)ethoxy]-2-methylpropane

Chemical Property:

• Vapor Pressure: 0.000278mmHg at 25°C
• Boiling Point: 200.6°Cat760mmHg
• Flash Point: 72.8°C
• PSA: 27.69000
• Density: 0.898g/cm³
• LogP: 1.46450
• XLogP3: 0.6
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 7
• Exact Mass: 176.14124450
• Heavy Atom Count: 12
• Complexity: 96.4

Purity/Quality:

98%,99%, ^*data from raw suppliers

2-[2-(2-METHOXYETHOXY)ETHOXY]-2-METHYL-PROPANE 95.00% ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36/37/39

MSDS Files:

Useful:

• Canonical SMILES: CC(C)(C)OCCOCCOC

Technology Process of 2-[2-(2-Methoxyethoxy)ethoxy]-2-methylpropane

There total 3 articles about 2-[2-(2-Methoxyethoxy)ethoxy]-2-methylpropane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

methylene chloride (74-87-3) + diethylene glycol mono(tert-butyl)ether (110-09-8) → diethylene glycol methyl tert-butyl ether (52788-79-1)

Guidance literature:

diethylene glycol mono(tert-butyl)ether; With potassium hydroxide; at 50 ℃; for 1h; under 600.06 Torr; Autoclave;

methylene chloride; at 60 ℃; for 2h; under 750.075 - 4500.45 Torr; Pressure; Temperature; Reagent/catalyst; Inert atmosphere;

Reference yield:

2-(2-methoxyethoxy)ethyl alcohol (111-77-3,95507-80-5) + 2-t-butoxy-1-methylpyridinium triflate → diethylene glycol methyl tert-butyl ether (52788-79-1)

Guidance literature:

at 23 ℃; for 1.5h; Solvent; Inert atmosphere; Cooling with ice;

DOI:10.1016/j.tetlet.2014.11.011

Reference yield:

2-(2-methoxyethoxy)ethyl alcohol (111-77-3,95507-80-5) + t-butyl bromide (507-19-7) → diethylene glycol methyl tert-butyl ether (52788-79-1)

Guidance literature:

With sodium hydride; Heating;

upstream raw materials:

2-(2-methoxyethoxy)ethyl alcohol

t-butyl bromide

methylene chloride

diethylene glycol mono(tert-butyl)ether

Refernces

• 1、 Salvati, Anna E.,Hubley, Christian T.,Albiniak, Philip A.. "Acid- and isobutylene-free synthesis of t-butyl ethers by in situ formation of 2-t-butoxy-1-methylpyridinium triflate". supporting information. p. 7133 - 7135. Retrieved 2015/01/08.