Chemical Property of Guanabenz
Chemical Property:
- Vapor Pressure:8.63E-07mmHg at 25°C
- Melting Point:227-229° (dec)
- Boiling Point:405.7°Cat760mmHg
- PKA:pKa 8.1 (Uncertain)
- Flash Point:199.1°C
- PSA：74.26000
- Density:1.49g/cm3
- LogP:3.00130
- XLogP3:1.7
- Hydrogen Bond Donor Count:2
- Hydrogen Bond Acceptor Count:2
- Rotatable Bond Count:2
- Exact Mass:230.0126017
- Heavy Atom Count:14
- Complexity:228
- Purity/Quality:
-
99%, *data from raw suppliers
N-(2,6-DICHLOROBENZYLIDENEAMINO)GUANIDINE Aldrich *data from reagent suppliers
Safty Information:
- Pictogram(s):
Xn
- Hazard Codes:Xn
- Statements:
20/21/22-62
- Safety Statements:
22-36/37/39
- MSDS Files:
-
Total 1 MSDS from other Authors
Useful:
- Canonical SMILES:C1=CC(=C(C(=C1)Cl)C=NN=C(N)N)Cl
- Recent ClinicalTrials:Oral Guanabenz for Multiple Sclerosis
- Recent EU Clinical Trials:A Study to Explore the Safety, Tolerability, Pharmacokinetic Profile, and Potential Efficacy of Guanabenz in Patients With Early Childhood Onset Vanishing White Matter (VWM)
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Description
Guanabenz is an α2-adrenergic agonist that exhibits pronounced hypotensive action, and
that is associated with a reduction of overall peripheral vascular resistance, decline in frequency
of cardiac contractions, and reduced cardiac output.
-
Uses
alpha agonists It is used both independently and in combination with oral diuretics for treating various
degrees of hypertension.
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Therapeutic Function
Antihypertensive
