3-(3-(4-(4-Chlorophenyl)-4-hydroxy-1-piperidinyl)propyl)-2-(4-methylphenyl)-4-thiazolidinone

Base Information

Chemical Name:3-(3-(4-(4-Chlorophenyl)-4-hydroxy-1-piperidinyl)propyl)-2-(4-methylphenyl)-4-thiazolidinone
CAS No.:182188-92-7
Molecular Formula:C₂₄H₂₉ClN₂O₂S
Molecular Weight:445.025
Hs Code.:
DSSTox Substance ID:DTXSID90939537
Nikkaji Number:J861.526H
Mol file:182188-92-7.mol

Synonyms:182188-92-7;3-(3-(4-(4-Chlorophenyl)-4-hydroxy-1-piperidinyl)propyl)-2-(4-methylphenyl)-4-thiazolidinone;4-Thiazolidinone, 3-(3-(4-(4-chlorophenyl)-4-hydroxy-1-piperidinyl)propyl)-2-(4-methylphenyl)-;3-[3-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]propyl]-2-(4-methylphenyl)-1,3-thiazolidin-4-one;3-[3-[4-(4-chlorophenyl)-4-hydroxy-1-piperidyl]propyl]-2-(4-methylphen yl)thiazolidin-4-one;3-{3-[4-(4-Chlorophenyl)-4-hydroxypiperidin-1-yl]propyl}-2-(4-methylphenyl)-1,3-thiazolidin-4-one;C24H29ClN2O2S;DTXSID90939537;AHRPIRMUYVNIFK-UHFFFAOYSA-N;C24-H29-Cl-N2-O2-S;LS-151647;2-p-Tolyl-3-[3-[4-hydroxy-4-(4-chlorophenyl)piperidino]propyl]thiazolidin-4-one

Suppliers and Price of 3-(3-(4-(4-Chlorophenyl)-4-hydroxy-1-piperidinyl)propyl)-2-(4-methylphenyl)-4-thiazolidinone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
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Total 0 raw suppliers

Chemical Property of 3-(3-(4-(4-Chlorophenyl)-4-hydroxy-1-piperidinyl)propyl)-2-(4-methylphenyl)-4-thiazolidinone

Chemical Property:

Vapor Pressure:3.37E-18mmHg at 25°C
Boiling Point:657.8°Cat760mmHg
Flash Point:351.6°C
PSA：69.08000
Density:1.252g/cm³
LogP:4.47190
XLogP3:4.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:6
Exact Mass:444.1638270
Heavy Atom Count:30
Complexity:568

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC=C(C=C1)C2N(C(=O)CS2)CCCN3CCC(CC3)(C4=CC=C(C=C4)Cl)O

Technology Process of 3-(3-(4-(4-Chlorophenyl)-4-hydroxy-1-piperidinyl)propyl)-2-(4-methylphenyl)-4-thiazolidinone

There total 4 articles about 3-(3-(4-(4-Chlorophenyl)-4-hydroxy-1-piperidinyl)propyl)-2-(4-methylphenyl)-4-thiazolidinone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 193882-56-3
2-{3-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-propyl}-isoindole-1,3-dione

: 182188-92-7
3-{3-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-propyl}-2-p-tolyl-thiazolidin-4-one

Guidance literature:: Multi-step reaction with 3 steps

1: 85 percent / N₂H₄*H₂O / methanol / 4 h / Heating

2: benzene / Heating

3: benzene / Heating

With hydrazine hydrate; In methanol; benzene;

Reference yield:

: 39512-49-7
4-(4-chlorophenyl)-4-hydroxypiperidine

: 182188-92-7
3-{3-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-propyl}-2-p-tolyl-thiazolidin-4-one

Guidance literature:: Multi-step reaction with 4 steps

1: 78 percent / Et₃N / acetonitrile / 48 h / Ambient temperature

2: 85 percent / N₂H₄*H₂O / methanol / 4 h / Heating

3: benzene / Heating

4: benzene / Heating

With hydrazine hydrate; triethylamine; In methanol; acetonitrile; benzene;