4-(4-Hydroxyphenyl)-3-buten-2-one

Base Information

Chemical Name:4-(4-Hydroxyphenyl)-3-buten-2-one
CAS No.:3160-35-8
Molecular Formula:C₁₀H₁₀O₂
Molecular Weight:162.188
Hs Code.:
Wikidata:Q105189467
Mol file:3160-35-8.mol

Synonyms:4-(4-Hydroxyphenyl)-3-buten-2-one;4-hydroxy-benzalacetone;4-Hydroxybenzilideneacetone;AKOS017269826;4-(4-hydroxy-phenyl)-but-3-en-2-one;FT-0618702;H1564

Suppliers and Price of 4-(4-Hydroxyphenyl)-3-buten-2-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4-Hydroxybenzylideneacetone
250mg
$ 80.00

TRC
4-Hydroxybenzylideneacetone
5g
$ 180.00

TCI Chemical
4-(4-Hydroxyphenyl)-3-buten-2-one >98.0%(GC)
5g
$ 91.00

Sigma-Aldrich
1-(4-HYDROXYBENZYLIDENE)ACETONE AldrichCPR
250mg
$ 144.00

ChemScene
4-Hydroxystyrylmethylketone ≥98.0%
5g
$ 90.00

ChemScene
4-Hydroxystyrylmethylketone ≥98.0%
10g
$ 175.00

Atlantic Research Chemicals
4-Hydroxybenzylideneacetone 95%
1gm:
$ 24.74

American Custom Chemicals Corporation
4-HYDROXYBENZYLIDENEACETONE 95.00%
500G
$ 5673.59

American Custom Chemicals Corporation
4-HYDROXYBENZYLIDENEACETONE 95.00%
250G
$ 5044.43

American Custom Chemicals Corporation
4-HYDROXYBENZYLIDENEACETONE 95.00%
100G
$ 2784.14

Total 28 raw suppliers

Chemical Property of 4-(4-Hydroxyphenyl)-3-buten-2-one

Chemical Property:

Vapor Pressure:0.000198mmHg at 25°C
Melting Point:108-111°C
Refractive Index:1.599
Boiling Point:318.1 °C at 760 mmHg
PKA:9.88±0.26(Predicted)
Flash Point:134.8 °C
PSA：37.30000
Density:1.138 g/cm³
LogP:1.99440
Storage Temp.:Refrigerator
Solubility.:Optimally soluble in aqueous solvents.
XLogP3:1.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:162.068079557
Heavy Atom Count:12
Complexity:176

Purity/Quality:

97% ^*data from raw suppliers

4-Hydroxybenzylideneacetone ^*data from reagent suppliers

Safty Information:

Pictogram(s): R36/37/38:Irritating to eyes, respiratory system and skin.;
Hazard Codes:R36/37/38:Irritating to eyes, respiratory system and skin.;
Statements: 36/37/38
Safety Statements: 26-37

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(=O)C=CC1=CC=C(C=C1)O
Uses 4-Hydroxybenzylideneacetone is used in the synthesis of 4-(4-hydroxy-phenyl)-butan-2-one. This reaction needs the reagents of cyclohexane and AlCl3, and the solvent of CH2Cl2.

Technology Process of 4-(4-Hydroxyphenyl)-3-buten-2-one

There total 14 articles about 4-(4-Hydroxyphenyl)-3-buten-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 123-08-0,65581-83-1
4-hydroxy-benzaldehyde

: 1439-36-7
1-triphenylphosphoranylidene-2-propanone

: 22214-30-8,59417-71-9,3160-35-8
4-(4'-hydroxyphenyl)but-3-en-2-one

Guidance literature:: In N,N-dimethyl-formamide; at 210 ℃; Continuous flow;
DOI:10.1021/op2001047

Reference yield: 87.1%

: 123-08-0,65581-83-1
4-hydroxy-benzaldehyde

: 67-64-1
acetone

: 22214-30-8,59417-71-9,3160-35-8
4-(4'-hydroxyphenyl)but-3-en-2-one

Guidance literature:: With sodium hydroxide; In water; at 0 - 20 ℃; for 10.5h;

Reference yield: 78.0%

: 540-38-5
p-Iodophenol

: 78-94-4,25038-87-3
methyl vinyl ketone

: 22214-30-8,59417-71-9,3160-35-8
4-(4'-hydroxyphenyl)but-3-en-2-one

Guidance literature:: With palladium diacetate; caesium carbonate; In water; N,N-dimethyl-formamide; at 160 ℃; Microwave irradiation;
DOI:10.1021/op2001047