1-[2-Oxo-2-(4-phenylpiperazin-1-yl)ethyl]pyrrolidine-2,5-dione

Base Information

Chemical Name:1-[2-Oxo-2-(4-phenylpiperazin-1-yl)ethyl]pyrrolidine-2,5-dione
CAS No.:65349-00-0
Molecular Formula:C16H19N3O3
Molecular Weight:301.345
Hs Code.:
ChEMBL ID:CHEMBL1834294
DSSTox Substance ID:DTXSID30495501
Wikidata:Q82343664

Synonyms:65349-00-0;1-[2-Oxo-2-(4-phenylpiperazin-1-yl)ethyl]pyrrolidine-2,5-dione;Oprea1_871775;CHEMBL1834294;DTXSID30495501

Suppliers and Price of 1-[2-Oxo-2-(4-phenylpiperazin-1-yl)ethyl]pyrrolidine-2,5-dione

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 1-[2-Oxo-2-(4-phenylpiperazin-1-yl)ethyl]pyrrolidine-2,5-dione

Chemical Property:

XLogP3:0.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:301.14264148
Heavy Atom Count:22
Complexity:436

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CC(=O)N(C1=O)CC(=O)N2CCN(CC2)C3=CC=CC=C3

Technology Process of 1-[2-Oxo-2-(4-phenylpiperazin-1-yl)ethyl]pyrrolidine-2,5-dione

There total 3 articles about 1-[2-Oxo-2-(4-phenylpiperazin-1-yl)ethyl]pyrrolidine-2,5-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 92-54-6
4-phenyl-1-piperazine

: C₉H₉N₃O₃

: 65349-00-0
1-[2-oxo-2-(4-phenylpiperazin-1-yl)ethyl]pyrrolidine-2,5-dione

Guidance literature:: In N,N-dimethyl-formamide; at 20 ℃; for 24h;
DOI:10.1016/j.bmcl.2011.07.118

Reference yield:

: 5626-41-5
2-(2,5-dioxopyrrolidin-1-yl)acetic acid

: 65349-00-0
1-[2-oxo-2-(4-phenylpiperazin-1-yl)ethyl]pyrrolidine-2,5-dione

Guidance literature:: Multi-step reaction with 2 steps

1: N,N-dimethyl-formamide / 0.5 h / 20 °C

2: N,N-dimethyl-formamide / 24 h / 20 °C

In N,N-dimethyl-formamide;
DOI:10.1016/j.bmcl.2011.07.118