Technology Process of Benzene, 1-chloro-4-[(pentafluoroethyl)thio]-
There total 4 articles about Benzene, 1-chloro-4-[(pentafluoroethyl)thio]- which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
pentafluoropropionic acid;
With
potassium tert-butylate;
In
ethanol;
for 1h;
4-chlorophenyl thiocyanate;
With
iron(III) chloride;
In
N,N-dimethyl-formamide;
at 140 ℃;
for 16h;
DOI:10.1016/j.jfluchem.2016.12.006
- Guidance literature:
-
4-Chlorophenylboronic acid;
With
carbon disulfide; potassium phosphate; 2-fluoropyridine; copper(I) thiocyanate; sulfur; silver carbonate;
In
N,N-dimethyl-formamide;
for 0.5h;
Glovebox;
Inert atmosphere;
Molecular sieve;
Sealed tube;
trimethyl(pentafluoroethyl)silane;
In
N,N-dimethyl-formamide;
at 70 ℃;
for 24h;
Glovebox;
Inert atmosphere;
Molecular sieve;
Sealed tube;
DOI:10.1016/j.jfluchem.2017.07.008
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: tetrafluoroboric acid; tert.-butylnitrite / ethanol; water / 1 h / 0 - 20 °C
1.2: 0 - 20 °C
2.1: potassium tert-butylate / ethanol / 1 h
2.2: 16 h / 140 °C
With
tetrafluoroboric acid; tert.-butylnitrite; potassium tert-butylate;
In
ethanol; water;
DOI:10.1016/j.jfluchem.2016.12.006
