3226-37-7

Basic information

• Product Name: 4-Chlorophenyl thiocyanate
• Synonyms: 4-Chlorophenyl thiocyanate;Thiocyanic acid 4-chlorophenyl ester
• CAS NO: 3226-37-7
• Molecular Formula: C₇H₄ClNS
• Molecular Weight: 169.63
• Mol File: 3226-37-7.mol
• Article Data: 31

Chemical Properties

• Boiling Point: 263.7°C at 760 mmHg
• Flash Point: 113.3°C
• Appearance: /
• Density: 1.35g/cm³
• Vapor Pressure: 0.0101mmHg at 25°C
• Refractive Index: 1.621
• CAS DataBase Reference: 4-Chlorophenyl thiocyanate(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Chlorophenyl thiocyanate(3226-37-7)
• EPA Substance Registry System: 4-Chlorophenyl thiocyanate(3226-37-7)

Safety Data

• Hazardous Substances Data: 3226-37-7(Hazardous Substances Data)

Usage

InChI:InChI=1/C7H4ClNS/c8-6-1-3-7(4-2-6)10-5-9/h1-4H

Upstream product

• 1142-19-4 4,4'-dichlorodiphenyl disulfide 
• 74-90-8 hydrogen cyanide 
• 2942-58-7 diethyl cyanophosphonate 
• 14752-66-0 sodium p-chlorobenzenesulphinate 
• 71452-03-4 C₃₁H₂₃ClN⁽¹⁺⁾*CNS^(1-) 
• 637-87-6 1-Chloro-4-iodobenzene 
• 1111-67-7 copper(I) thiocyanate 
• 333-20-0 potassium thioacyanate 
• 447-14-3 1,2,2-trifluorostyrene 
• 673-41-6 p-chlorobenzenediazonium tetrafluoroborate 
• 1146-44-7 4,4'-dichlorophenyl thiosulfonate 
• 151-50-8 potassium cyanide 
• 17333-85-6 4-chlorophenyldiazonium salt 
• 540-72-7 sodium thiocyanide 

Downstream Products

• 1142-19-4 4,4'-dichlorodiphenyl disulfide 
• 6803-43-6 4-chloro-2-nitro-phenyl thiocyanate 
• 95062-74-1 S-(4-chlorophenyl) thiocarbamate 
• 35878-13-8 C₈H₈ClNOS 
• 14157-35-8 2-(4-chloro-phenylsulfanyl)-4-methyl-3-oxa-1-aza-spiro[5.5]undeca-1,4-diene 
• 76665-93-5 p-chlorophenyl perfluorobutyl sulfide 
• 504-60-9 penta-1,3-diene 
• 109-67-1 1-penten 
• 109-68-2 2-pentene 
• 592-76-7 1-Heptene 
• 1002-26-2 1,3-heptadiene 
• 592-41-6 1-hexene 
• 111-66-0 oct-1-ene 
• 407-16-9 4-chlorophenyl trifluoromethyl sulfide 

Relevant articles and documents

Facile Synthesis of Organic Thiocyanates from Organozinc(II) Thiocyanates and N-chlorosuccinimide

The reaction of organozinc(II) compounds, generated in situ from organolithiums and zinc(II) thiocyaniate, with N-chlorosuccinimide (NCS) afforded the corresponding organic thiocyanates in good yields.

An electrochemical method for deborylative seleno/thiocyanation of arylboronic acids under catalyst- And oxidant-free conditions

An electrochemical deborylative seleno/thiocyanation of arylboronic acids has been well established to synthesize the corresponding aryl seleno/thiocyanates with good functional group tolerance under ambient conditions. A gram-scale reaction has been performed to highlight the advantages of the protocol. Preliminary mechanistic studies indicate that the oxidation of the seleno/thiocyanate anion occurs prior to that of the arylboronic acid substrate in galvanostatic mode, and that free radicals are involved in the process.

Direct Photocatalytic S-H Bond Cyanation with Green cN Source

Herein we report a novel C-S bond cleavage and reconstruction strategy for the synthesis of thiocyanates through direct photocatalytic S-H bond cyanation from thiols and inorganic thiocyanate salts. In our strategy, the unprecedented example of cutting off C-S bond of SCN- to deliver the green CN sources is demonstrated. This transformation features nontoxic and inexpensive CN sources, available starting materials, metal-/base-/ligand-/peroxide-free, high step economy and mild conditions. It leads to the construction of various thiocyanates and some medicinally and biologically active thiocyanate-containing molecules.