Cyclohexanecarboxylic acid, 1-methyl-, ethyl ester

Base Information

• Chemical Name: Cyclohexanecarboxylic acid, 1-methyl-, ethyl ester
• CAS No.: 6553-85-1
• Molecular Formula: C10H18O2
• Molecular Weight: 170.252
• Mol file: 6553-85-1.mol

Synonyms:ethyl 1-methylcyclohexanecarboxylate;1-Methyl-cyclohexancarbonsaeure-aethylester;1-Methyl-cyclohexan-carbonsaeure-aethylester;1-Methylcyclohexancarbonsaeureethylester;1-Methyl-cyclohexancarbonsaeure-ethylester;1-Methyl-cyclohexancarbonsaeure-(1)-ethylester;

Chemical Property of Cyclohexanecarboxylic acid, 1-methyl-, ethyl ester

Chemical Property:

• Boiling Point: 82-83 °C(Press: 12 Torr)
• PSA: 26.30000
• Density: 0.951±0.06 g/cm3(Predicted)
• LogP: 2.51990

Purity/Quality:

97% ^*data from raw suppliers

ethyl1-methylcyclohexane-1-carboxylate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Cyclohexanecarboxylic acid, 1-methyl-, ethyl ester

There total 8 articles about Cyclohexanecarboxylic acid, 1-methyl-, ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

ethanol (64-17-5) + carbon monoxide (201230-82-2) + 1-chloro-1-methylcyclohexane (931-78-2) → 1-methyl-cyclohexanecarboxylic acid ethyl ester (6553-85-1)

Guidance literature:

With antimonypentachloride; In dichloromethane; at -70 ℃;

DOI:10.1246/bcsj.44.2001

Reference yield:

2-chloro-1-cyclohexyl-1-ethanone (1892-09-7) → 1-methyl-cyclohexanecarboxylic acid ethyl ester (6553-85-1)

Guidance literature:

With ethanol; sodium ethanolate;

DOI:10.1021/ja01630a008

Reference yield:

ethyl 1-methyl-2-oxocyclohexancarboxylate (66088-37-7,5453-94-1) → 1-methyl-cyclohexanecarboxylic acid ethyl ester (6553-85-1)

Guidance literature:

With methylthiol; zinc(II) chloride; Erwaermen des Reaktionsprodukts mit Raney-Nickel in Aethanol;

DOI:10.1021/ja01165a527

upstream raw materials:

2-chloro-1-cyclohexyl-1-ethanone

ethyl 1-methyl-2-oxocyclohexancarboxylate

1-bromomethyl-cyclohexanecarboxylic acid ethyl ester

ethanol

Downstream raw materials:

1-methyl-1-cyclohexanecarboxylic acid

1-(4-methoxybenzyl)-N-(quinolin-8-yl)cyclohexanecarboxamide