1H-Benzimidazole,5-chloro-2-(1-methylethyl)-(9CI)

Base Information

• Chemical Name: 1H-Benzimidazole,5-chloro-2-(1-methylethyl)-(9CI)
• CAS No.: 4886-29-7
• Molecular Formula: C10H11 Cl N2
• Molecular Weight: 194.664
• Hs Code.: 2933990090
• Mol file: 4886-29-7.mol

Synonyms:1H-Benzimidazole,5-chloro-2-(1-methylethyl)- (9CI); Benzimidazole, 5(or 6)-chloro-2-isopropyl-(7CI); Benzimidazole, 5-chloro-2-isopropyl- (8CI);2-Isopropyl-5-chloro-1H-benzimidazole; 2-Isopropyl-5-chlorobenzimidazole;5-Chloro-2-isopropylbenzimidazole

Chemical Property of 1H-Benzimidazole,5-chloro-2-(1-methylethyl)-(9CI)

Chemical Property:

• Vapor Pressure: 3.1E-05mmHg at 25°C
• Boiling Point: 366.4°C at 760 mmHg
• Flash Point: 206.9°C
• PSA: 28.68000
• Density: 1.238g/cm³
• LogP: 3.33970
• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

97% ^*data from raw suppliers

6-chloro-2-isopropyl-1H-benzo[d]imidazole 98% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1H-Benzimidazole,5-chloro-2-(1-methylethyl)-(9CI)

There total 7 articles about 1H-Benzimidazole,5-chloro-2-(1-methylethyl)-(9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

2-azido-4-chlorobenzenamine (17537-17-6) + isobutyraldehyde (78-84-2) → 5-chloro-2-(1-methylethyl)benzimidazole (4886-29-7)

Guidance literature:

In ethanol; for 24h; Heating;

DOI:10.1080/00397910600941497

Reference yield: 70.0%

4-Chloro-1,2-phenylenediamine (95-83-0) + isobutyric Acid (79-31-2) → 5-chloro-2-(1-methylethyl)benzimidazole (4886-29-7)

Guidance literature:

With hydrogenchloride; for 4h; Heating;

Reference yield: 66.0%

5-Chloro-2-azidoaniline (75458-14-9) + isobutyraldehyde (78-84-2) → 5-chloro-2-(1-methylethyl)benzimidazole (4886-29-7)

Guidance literature:

In ethanol; for 24h; Heating;

DOI:10.1080/00397910600941497

upstream raw materials:

N-(2-Amino-4-chloro-phenyl)-isobutyramide

4-Chloro-1,2-phenylenediamine

isobutyric Acid

2-azido-4-chlorobenzenamine