1,3,4-Oxadiazole-2(3H)-thione, 3-benzoyl-5-phenyl-

Base Information

Chemical Name:1,3,4-Oxadiazole-2(3H)-thione, 3-benzoyl-5-phenyl-
CAS No.:65715-09-5
Molecular Formula:C15H10N2O2S
Molecular Weight:282.323
Hs Code.:
DSSTox Substance ID:DTXSID50433445
Nikkaji Number:J1.645.938K
Wikidata:Q82247596

Synonyms:65715-09-5;Phenyl(5-phenyl-2-thioxo-1,3,4-oxadiazol-3(2H)-yl)methanone;1,3,4-Oxadiazole-2(3H)-thione, 3-benzoyl-5-phenyl-;SCHEMBL7696311;DTXSID50433445;3-Benzoyl-5-phenyl-1,3,4-oxadiazole-2(3H)-thione

Suppliers and Price of 1,3,4-Oxadiazole-2(3H)-thione, 3-benzoyl-5-phenyl-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 1,3,4-Oxadiazole-2(3H)-thione, 3-benzoyl-5-phenyl-

Chemical Property:

XLogP3:3.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:282.04629874
Heavy Atom Count:20
Complexity:424

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)C2=NN(C(=S)O2)C(=O)C3=CC=CC=C3

Technology Process of 1,3,4-Oxadiazole-2(3H)-thione, 3-benzoyl-5-phenyl-

There total 6 articles about 1,3,4-Oxadiazole-2(3H)-thione, 3-benzoyl-5-phenyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 65-85-0,8013-63-6
benzoic acid

: 122350-19-0
3,3'-carbonylbis<5-phenyl-1,3,4-oxadiazole-2(3H)-thione>

: 3004-42-0
5-phenyl-1,3,4-oxadiazole-2(3H)-thione

: 65715-09-5
2-phenyl-3-benzoyl-1,3,4-oxadiazole-2-(3H)-thione

Guidance literature:: With pyridine; In various solvent(s); for 2h; Ambient temperature;
DOI:10.1246/bcsj.62.539

Reference yield: 70.0%

: 463-71-8
thiophosgene

: 112225-87-3
benzoic acid N'-benzoyl-N-tert-butylhydrazide

: 65715-09-5
2-phenyl-3-benzoyl-1,3,4-oxadiazole-2-(3H)-thione

Guidance literature:: benzoic acid N'-benzoyl-N-tert-butylhydrazide; With potassium tert-butylate; In tetrahydrofuran; at 20 ℃;

thiophosgene; In tetrahydrofuran; ethyl acetate; at -78 ℃;
DOI:10.1055/s-2001-17703

Reference yield:

: 98-88-4
benzoyl chloride

: 65715-09-5
2-phenyl-3-benzoyl-1,3,4-oxadiazole-2-(3H)-thione

Guidance literature:: Multi-step reaction with 2 steps

1.1: DIEA / CH₂Cl₂; ethanol / 20 °C

2.1: tBuOK / tetrahydrofuran / 20 °C

2.2: 70 percent / tetrahydrofuran; ethyl acetate / -78 °C

With potassium tert-butylate; N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; ethanol; dichloromethane;
DOI:10.1055/s-2001-17703