Phosphine sulfide, diethyl-

Base Information

• Chemical Name: Phosphine sulfide, diethyl-
• CAS No.: 6591-06-6
• Molecular Formula: C4H11PS
• Molecular Weight: 122.171
• DSSTox Substance ID: DTXSID00453678
• Wikidata: Q82274875
• Mol file: 6591-06-6.mol

Synonyms:6591-06-6;Phosphine sulfide, diethyl-;diethyl thiono-phosphorus;SCHEMBL7196270;DTXSID00453678

Chemical Property of Phosphine sulfide, diethyl-

Chemical Property:

• XLogP3: 1.5
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 2
• Exact Mass: 121.02408349
• Heavy Atom Count: 6
• Complexity: 45.5

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC[P+](=S)CC

Technology Process of Phosphine sulfide, diethyl-

There total 1 articles about Phosphine sulfide, diethyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

diethyl(4-(dimethylamino)benzoyl)phosphine sulfide (1251445-57-4) + 4-methoxy-phenol (150-76-5) → diethylphosphine sulfide (6591-06-6) + 4-methoxyphenyl 4-(dimethylamino)benzoate

Guidance literature:

With hydridotetakis(triphenylphosphine)rhodium(I); 1,2-bis-(diphenylphosphino)ethane; In chlorobenzene; for 4h; Inert atmosphere; Reflux;

DOI:10.1016/j.tet.2011.07.031

Reference yield: 95.0%

diethylphosphine sulfide (6591-06-6) + tetrakis(methyldiphenylphosphine)platinum(0) (27121-53-5) → [(μ-SPEt2)2(PMePh2)2diplatinum(I)] (54020-33-6)

Guidance literature:

In benzene; byproducts: H2, PPh2Me; Ar-atmosphere; equimolar amts., stirring for 10 h (pptn.); collection (filtration), washing (Et2O), drying (vac.), recrystn. (CHCl3/C6H14);

Reference yield: 65.0%

diethylphosphine sulfide (6591-06-6) + ICo(CO)2(P(C6H11)3)2 (112792-41-3) + N-ethyl-N,N-diisopropylamine (7087-68-5) → N,N-diisopropylethylamine hydroiodide + dicarbonyl(η2-diethylthiophosphinito)(tricyclohexylphosphane)cobalt(I) (112792-45-7) + tricyclohexylphosphine (2622-14-2)

Guidance literature:

In toluene; under N2 or Ar, exclusion of oxygen and moisture, addn. of soln. of amine in toluene to a part of soln. of Co compound in toluene at 25°C, addn. of the rest of this soln. together with (C2H5)2HPS during 2 h, 15 h; decantation, evapn. of solvent in vac., residue dissolved in n-hexane, filtration of ((Et)(i-Pr)2NH)I and excess ICo(CO)2(P(C6H11)3)2, crystn. at -5°C, recrystn. from n-hexane at -5°C; elem. anal.;

upstream raw materials:

diethyl(4-(dimethylamino)benzoyl)phosphine sulfide

4-methoxy-phenol

Downstream raw materials:

C₁₇H₂₀PS₂

dicarbonyl(η2-diethylthiophosphinito)(triphenylphosphane)cobalt(I)

dicarbonyl(η2-diethylthiophosphinito)(tricyclohexylphosphane)cobalt(I)

tricyclohexylphosphine

Refernces