Trimethylphosphoramide

Base Information

Chemical Name:Trimethylphosphoramide
CAS No.:6326-72-3
Molecular Formula:C₃H₁₂N₃OP
Molecular Weight:137.122
Hs Code.:
NSC Number:30694
UNII:B8899ZB75V
DSSTox Substance ID:DTXSID80212649
Nikkaji Number:J894.155F
Wikidata:Q83087805
Mol file:6326-72-3.mol

Synonyms:Trimethylphosphoramide;6326-72-3;N,N',N''-Trimethylphosphoramide;NSC30694;B8899ZB75V;NSC-30694;CCRIS 7900;N-[bis(methylamino)phosphoryl]methanamine;NSC 30694;AI3-24910;Phosphoric triamide, N,N',N-trimethyl-;Phosphoric triamide, N,N',N"-trimethyl-;UNII-B8899ZB75V;SCHEMBL8853603;DTXSID80212649;Phosphoric triamide, N,N',N''-trimethyl-

Suppliers and Price of Trimethylphosphoramide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 6 raw suppliers

Chemical Property of Trimethylphosphoramide

Chemical Property:

Boiling Point:179.5oC at 760 mmHg
Flash Point:62.3oC
PSA：62.97000
Density:1.065g/cm3
LogP:0.92540
XLogP3:-1.3
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:137.07179901
Heavy Atom Count:8
Complexity:85.7

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CNP(=O)(NC)NC

Technology Process of Trimethylphosphoramide

There total 2 articles about Trimethylphosphoramide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 74-89-5
methylamine

: 6326-72-3
Phosphorsaeure-tris(methylamid)

Guidance literature:: With chloroform; trichlorophosphate;
DOI:10.1021/jo01092a007

Reference yield:

: 6326-72-3
Phosphorsaeure-tris(methylamid)

Guidance literature:: Methylamin, POCl3; neben Methylammoniummonochlorid;
DOI:10.1021/ic50001a017

Reference yield: 49.0%

: 6326-72-3
Phosphorsaeure-tris(methylamid)

: 7732-18-5
water

: 544-97-8
dimethyl zinc(II)

: 108-88-3,15644-74-3,16713-13-6
toluene

: 883551-04-0
(Zn4(μ4-O)[OP(NMe)(NHMe)2]4[OP(NMe)2(NHMe)])2*(toluene)

Guidance literature:: In toluene; under Ar; a soln. of ZnMe2 (1.18 mmol) in toluene was added dropwise to a soln. of OP(NHMe)3 (1.18 mmol) in toluene at 22°C; the soln. was heated at reflux for 24 h; the vol. was reduced to one-half and the residue was placed in the freezer; after 7 d at -15°C crystals were obtained; elem. anal.;
DOI:10.1139/v05-183