Ethyl 2-hydrazinyl-4-methylpyrimidine-5-carboxylate

Base Information

Chemical Name:Ethyl 2-hydrazinyl-4-methylpyrimidine-5-carboxylate
CAS No.:66373-46-4
Molecular Formula:C8H12N4O2
Molecular Weight:196.20600
Hs Code.:2933990090
European Community (EC) Number:968-236-5

Synonyms:Ethyl 2-hydrazinyl-4-methylpyrimidine-5-carboxylate;66373-46-4;MFCD09878516;Ethyl 2-hydrazino-4-methylpyrimidine-5-carboxylate;Ethyl 2-hydrazino-4-methyl-pyrimidine-5-carboxylate;SCHEMBL8398108;VBRMUJGUHAMQNU-UHFFFAOYSA-N;AKOS006311101;SB55779;AS-32698;CS-0225859;FT-0724494;2-hydrazino-4-methyl-5-ethoxycarbonylpyrimidine;EN300-125093;A867472;Ethyl2-hydrazinyl-4-methylpyrimidine-5-carboxylate

Suppliers and Price of Ethyl 2-hydrazinyl-4-methylpyrimidine-5-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Ethyl2-Hydrazinyl-4-methylpyrimidine-5-carboxylate
100mg
$ 90.00

TRC
Ethyl2-Hydrazinyl-4-methylpyrimidine-5-carboxylate
50mg
$ 65.00

Matrix Scientific
Ethyl 2-hydrazinyl-4-methylpyrimidine-5-carboxylate 95%
5g
$ 1071.00

Matrix Scientific
Ethyl 2-hydrazinyl-4-methylpyrimidine-5-carboxylate 95%
1g
$ 357.00

Matrix Scientific
Ethyl 2-hydrazinyl-4-methylpyrimidine-5-carboxylate 95%
500mg
$ 224.00

Frontier Specialty Chemicals
Ethyl2-hydrazino-4-methylpyrimidine-5-carboxylate 97%
1g
$ 271.00

Crysdot
Ethyl2-hydrazinyl-4-methylpyrimidine-5-carboxylate 95+%
5g
$ 612.00

Chemenu
Ethyl2-hydrazinyl-4-methylpyrimidine-5-carboxylate 95%
5g
$ 578.00

American Custom Chemicals Corporation
ETHYL 2-HYDRAZINYL-4-METHYLPYRIMIDINE-5-CARBOXYLATE 95.00%
1G
$ 369.60

Alichem
Ethyl2-hydrazinyl-4-methylpyrimidine-5-carboxylate
5g
$ 889.81

Total 9 raw suppliers

Chemical Property of Ethyl 2-hydrazinyl-4-methylpyrimidine-5-carboxylate

Chemical Property:

Melting Point:173-174 °C
Boiling Point:331.9±52.0 °C(Predicted)
PKA:5.47±0.40(Predicted)
PSA：90.13000
Density:1.34±0.1 g/cm3(Predicted)
LogP:1.02060
XLogP3:0.4
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:4
Exact Mass:196.09602564
Heavy Atom Count:14
Complexity:200

Purity/Quality:

97% ^*data from raw suppliers

Ethyl2-Hydrazinyl-4-methylpyrimidine-5-carboxylate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:
Statements: 20/21/22
Safety Statements: 24/25-36/37

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)C1=CN=C(N=C1C)NN

Technology Process of Ethyl 2-hydrazinyl-4-methylpyrimidine-5-carboxylate

There total 9 articles about Ethyl 2-hydrazinyl-4-methylpyrimidine-5-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 188781-08-0
2-chloro-4-methylpyrimidine-5-carboxylic acid ethyl ester

: 66373-46-4
2-hydrazino-4-methyl-pyrimidine-5-carboxylic acid ethyl ester

Guidance literature:: With hydrazine; In tetrahydrofuran;

Reference yield:

: 6319-01-3
ethyl 2-acetyl-3-ureido-2-propenoate

: 66373-46-4
2-hydrazino-4-methyl-pyrimidine-5-carboxylic acid ethyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: NaOEt / ethanol / 20 °C

2: POCl₃ / 3 h / Heating

3: hydrazine / tetrahydrofuran / 0.08 h / 20 °C

With sodium ethanolate; hydrazine; trichlorophosphate; In tetrahydrofuran; ethanol;
DOI:10.1016/S0960-894X(02)00517-6

Reference yield:

: 141-97-9
ethyl acetoacetate

: 66373-46-4
2-hydrazino-4-methyl-pyrimidine-5-carboxylic acid ethyl ester

Guidance literature:: Multi-step reaction with 4 steps

1: Heating

2: NaOEt / ethanol / 20 °C

3: POCl₃ / 3 h / Heating

4: hydrazine / tetrahydrofuran / 0.08 h / 20 °C

With sodium ethanolate; hydrazine; trichlorophosphate; In tetrahydrofuran; ethanol;
DOI:10.1016/S0960-894X(02)00517-6