Benzeneacetic acid, 4-methyl-a-(methylamino)-, hydrochloride

Base Information

• Chemical Name: Benzeneacetic acid, 4-methyl-a-(methylamino)-, hydrochloride
• CAS No.: 66380-03-8
• Molecular Formula: C10H13NO2.ClH
• Molecular Weight: 215.68

Synonyms:

Chemical Property of Benzeneacetic acid, 4-methyl-a-(methylamino)-, hydrochloride

Chemical Property:

Purity/Quality:

97% ^*data from raw suppliers

2-(Methylamino)-2-(4-methylphenyl)aceticacidhydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Benzeneacetic acid, 4-methyl-a-(methylamino)-, hydrochloride

There total 2 articles about Benzeneacetic acid, 4-methyl-a-(methylamino)-, hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

carbon monoxide (201230-82-2) + p-methylbenzylidene-methylamine (17972-13-3,29086-13-3,53699-34-6) → N-methyl-C-(4-methylphenyl)-glycine hydrochloride (66380-03-8)

Guidance literature:

carbon monoxide; p-methylbenzylidene-methylamine; In 1,4-dioxane; hexane; at 50 ℃; for 6h; under 41372.9 Torr;

With hydrogenchloride; for 24h; Further stages.; Heating;

DOI:10.1002/anie.200700646

Reference yield: 64.0%

potassium cyanide + methylamine hydrochloride (593-51-1) + 4-methyl-benzaldehyde (104-87-0) → N-methyl-C-(4-methylphenyl)-glycine hydrochloride (66380-03-8)

Guidance literature:

potassium cyanide; methylamine hydrochloride; 4-methyl-benzaldehyde; In methanol; water; for 4h;

With hydrogenchloride; In water; toluene; for 6h; Reflux;

DOI:10.1177/1178223420913330

Reference yield:

N-methyl-C-(4-methylphenyl)-glycine hydrochloride (66380-03-8) + 4-methyl-benzoyl chloride (874-60-2) → N-methyl-N-(4-methylbenzoyl)-C-(4-methylphenyl)-glycine

Guidance literature:

With sodium hydroxide; In tetrachloromethane; at 20 ℃; for 3h;

DOI:10.1016/S0040-4020(98)00668-1

upstream raw materials:

carbon monoxide

p-methylbenzylidene-methylamine

methylamine hydrochloride

4-methyl-benzaldehyde

Downstream raw materials:

N-benzoyl-N-methyl-C-(4-methylphenyl)-glycine

3-methyl-2,4-bis(4'-methylphenyl)-oxazolium-5-olate

diethyl-[4-(4-methoxy-phenyl)-5-(1-methyl-2,5-di-p-tolyl-2,5-dihydro-1H-pyrrol-3-yl)-1,1-dioxo-1H-1λ⁶-isothiazol-3-yl]-amine

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 66380-03-8 Benzeneacetic acid, 4-methyl-a-(methylamino)-, hydrochloride

Send

Send

Metric Ton KG G Pound L ML

Send

Send