2-phenyl-1,3-oxazinane

Base Information

• Chemical Name: 2-phenyl-1,3-oxazinane
• CAS No.: 17762-72-0
• Molecular Formula: C10H13 N O
• Molecular Weight: 163.219
• Mol file: 17762-72-0.mol

Synonyms:NSC 526552

Chemical Property of 2-phenyl-1,3-oxazinane

Chemical Property:

• Vapor Pressure: 0.00584mmHg at 25°C
• Boiling Point: 273.1°Cat760mmHg
• Flash Point: 105.3°C
• Density: 1.034g/cm³

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-phenyl-1,3-oxazinane

There total 3 articles about 2-phenyl-1,3-oxazinane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 36.0%

benzaldehyde (100-52-7) + propan-1-ol-3-amine (156-87-6) → 2-phenyl-tetrahydro-(2H)-1,3-oxazine (17762-72-0)

Guidance literature:

In ethanol; for 2h; Ambient temperature;

DOI:10.1021/jo00226a018

Reference yield:

→ 2-phenyl-tetrahydro-(2H)-1,3-oxazine (17762-72-0)

Guidance literature:

With potassium hydroxide;

Reference yield:

N-Benzyliden-3-hydroxy-1-propanamin (5433-11-4) → 2-phenyl-tetrahydro-(2H)-1,3-oxazine (17762-72-0)

Guidance literature:

In chloroform-d1; at 35 ℃; Equilibrium constant; Thermodynamic data; var. solvents and temp., ΔH⁰, ΔS⁰;

upstream raw materials:

N-Benzyliden-3-hydroxy-1-propanamin

benzaldehyde

propan-1-ol-3-amine

Downstream raw materials:

3,3'-bis-indolyl(phenyl)methane

1-phenyl-2,3,4,9-tetrahydro-1H-beta-carboline

N-benzylidene-2-(1H-indol-3-yl)ethylamine

diethyl 1,4-dihydro-2,6-dimethyl-1,4-diphenyl-3,5-pyridinedicarboxylate