methyl 3-(4-methoxyphenyl)-2-phenyl-propanoate

Base Information

• Chemical Name: methyl 3-(4-methoxyphenyl)-2-phenyl-propanoate
• CAS No.: 5448-41-9
• Molecular Formula: C17H18 O3
• Molecular Weight: 270.328
• Hs Code.: 2918990090
• Mol file: 5448-41-9.mol

Synonyms:Propionicacid, 3-(p-methoxyphenyl)-2-phenyl-, methyl ester (8CI); Hydrocinnamic acid,p-methoxy-a-phenyl-, methyl ester; NSC 17951

Chemical Property of methyl 3-(4-methoxyphenyl)-2-phenyl-propanoate

Chemical Property:

• Vapor Pressure: 1.81E-05mmHg at 25°C
• Boiling Point: 363.4°Cat760mmHg
• Flash Point: 151.8°C
• PSA: 35.53000
• Density: 1.106g/cm³
• LogP: 3.19450

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of methyl 3-(4-methoxyphenyl)-2-phenyl-propanoate

There total 4 articles about methyl 3-(4-methoxyphenyl)-2-phenyl-propanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

p-Methoxybenzyl bromide (2746-25-0) + benzeneacetic acid methyl ester (101-41-7) → methyl 3-(4'-methoxyphenyl)-2-phenylpropanoate (5448-41-9)

Guidance literature:

benzeneacetic acid methyl ester; With potassium tert-butylate; In tetrahydrofuran; at 0 ℃; for 0.25h;

p-Methoxybenzyl bromide; In tetrahydrofuran; at 5 - 20 ℃;

Reference yield:

diazomethane (186581-53-3,908094-01-9,334-88-3) + C16H13ClO3 (1262329-30-5) → C17H17ClO3 + methyl 3-(4'-methoxyphenyl)-2-phenylpropanoate (5448-41-9)

Guidance literature:

C₁₆H₁₃ClO₃; With palladium/alumina; hydrogen; In water; N,N-dimethyl-formamide; at 21.84 ℃; for 6h; under 750.075 Torr;

diazomethane; In diethyl ether;

DOI:10.1016/j.molcata.2010.09.013

Reference yield:

methanol (67-56-1) + 3-(4-methoxyphenyl)-2-phenylpropionic acid (4314-68-5) → methyl 3-(4'-methoxyphenyl)-2-phenylpropanoate (5448-41-9)

Guidance literature:

With sulfuric acid;

upstream raw materials:

methanol

3-(4-methoxyphenyl)-2-phenylpropionic acid

diazomethane

C₁₆H₁₃ClO₃

Downstream raw materials:

3-(4-methoxyphenyl)-2-phenylpropionic acid

(1R,3r,5S)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl 3-(4-methoxyphenyl)-2-phenylpropanoate