p-Hydroxyphenyl 2-pyridyl ketone

Base Information

Chemical Name:p-Hydroxyphenyl 2-pyridyl ketone
CAS No.:33077-70-2
Molecular Formula:C12H9 N O2
Molecular Weight:199.209
Hs Code.:2933399090
European Community (EC) Number:251-368-6
UNII:KU9QMQ3YG6
DSSTox Substance ID:DTXSID90186726
Nikkaji Number:J41.559F
Wikidata:Q83058094
Mol file:33077-70-2.mol

Synonyms:33077-70-2;p-Hydroxyphenyl 2-pyridyl ketone;4-(PYRIDINE-2-CARBONYL)PHENOL;(4-hydroxyphenyl)-pyridin-2-ylmethanone;(p-Hydroxyphenyl) 2-pyridyl ketone;KETONE, (p-HYDROXYPHENYL) 2-PYRIDYL;2-(p-Hydroxybenzoyl)pyridine;Methanone, (4-hydroxyphenyl)-2-pyridinyl-;Pyridine, 2-(p-hydroxybenzoyl)-;EINECS 251-368-6;KU9QMQ3YG6;BRN 1527976;UNII-KU9QMQ3YG6;SCHEMBL2485773;DTXSID90186726;Ketone, p-hydroxyphenyl 2-pyridyl;p-Hydroxyphenyl(2-pyridyl) ketone;MFCD01716461;AKOS006275931;BS-16884;LS-87243;(4-hydroxy-phenyl)-pyridin-2-yl-methanone;CS-0162272;(4-HYDROXYPHENYL)-2-PYRIDINYLMETHANONE;D80784;EN300-1663454;(4-HYDROXYPHENYL)(PYRIDIN-2-YL)METHANONE

Suppliers and Price of p-Hydroxyphenyl 2-pyridyl ketone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
P-HYDROXYPHENYL 2-PYRIDYL KETONE 95.00%
5MG
$ 497.89

AK Scientific
p-Hydroxyphenyl2-pyridylketone
5g
$ 4348.00

AK Scientific
p-Hydroxyphenyl2-pyridylketone
250mg
$ 826.00

AK Scientific
p-Hydroxyphenyl2-pyridylketone
50mg
$ 440.00

AK Scientific
p-Hydroxyphenyl2-pyridylketone
5mg
$ 235.00

Total 9 raw suppliers

Chemical Property of p-Hydroxyphenyl 2-pyridyl ketone

Chemical Property:

Vapor Pressure:8.5E-07mmHg at 25°C
Refractive Index:1.5880 (estimate)
Boiling Point:394.8°Cat760mmHg
Flash Point:192.5°C
PSA：50.19000
Density:1.251g/cm³
LogP:2.01820
Storage Temp.:Sealed in dry,Room Temperature
XLogP3:1.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:199.063328530
Heavy Atom Count:15
Complexity:222

Purity/Quality:

99% ^*data from raw suppliers

P-HYDROXYPHENYL 2-PYRIDYL KETONE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=NC(=C1)C(=O)C2=CC=C(C=C2)O

Technology Process of p-Hydroxyphenyl 2-pyridyl ketone

There total 8 articles about p-Hydroxyphenyl 2-pyridyl ketone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 69.0%

: 5029-67-4
2-iodopyridine

: 99-96-7
4-hydroxy-benzoic acid

: 33077-70-2
(4-hydroxyphenyl)(pyridin-2-yl)methanone

Guidance literature:: 4-hydroxy-benzoic acid; With isopropylmagnesium bromide; In tetrahydrofuran; 2-methyltetrahydrofuran; at 15 ℃; Inert atmosphere; Cooling with ice;

2-iodopyridine; In tetrahydrofuran; 2-methyltetrahydrofuran; Inert atmosphere;

With TurboGrignard; In tetrahydrofuran; 2-methyltetrahydrofuran; at 20 - 30 ℃; for 19h; Inert atmosphere;
DOI:10.1021/acs.joc.6b00194

Reference yield: 56.0%

: 26838-86-8
pyridine-2-carboxylic acid phenyl ester

: 22945-62-6
(2-hydroxyphenyl)(pyridin-2-yl)methanone

: 33077-70-2
(4-hydroxyphenyl)(pyridin-2-yl)methanone

Guidance literature:: With aluminium trichloride; at 160 ℃; for 4h;

Reference yield:

: 6305-18-6
2-(4-methoxybenzoyl)pyridine

: 33077-70-2
(4-hydroxyphenyl)(pyridin-2-yl)methanone

Guidance literature:: 2-(4-methoxybenzoyl)pyridine; With boron tribromide; In dichloromethane; at -78 - 20 ℃;

With sodium hydrogencarbonate; In dichloromethane;