Methyl 2-hydroxy-5-methyl-3-nitrobenzoate

Base Information

• Chemical Name: Methyl 2-hydroxy-5-methyl-3-nitrobenzoate
• CAS No.: 67191-44-0
• Molecular Formula: C9H9NO5
• Molecular Weight: 211.174
• Hs Code.: 2918290000
• DSSTox Substance ID: DTXSID00502978
• Wikidata: Q82356434

Synonyms:67191-44-0;Methyl 2-hydroxy-5-methyl-3-nitrobenzoate;Methyl 2-hydroxy-5-methyl-3-nitrobenzenecarboxylate;METHYL 2-HYDROXY-5-METHYL-3-NITROBENZOATE 95+%;SCHEMBL11067071;DTXSID00502978;ZQGOQALTCFDIHN-UHFFFAOYSA-N;MFCD14560553;AKOS005073737;ND-0003;Methyl2-hydroxy-5-methyl-3-nitrobenzoate;CS-0454778;FT-0681720;J-522028

Chemical Property of Methyl 2-hydroxy-5-methyl-3-nitrobenzoate

Chemical Property:

• PSA: 92.35000
• LogP: 1.91860
• Storage Temp.: 2-8°C
• XLogP3: 2.2
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 2
• Exact Mass: 211.04807239
• Heavy Atom Count: 15
• Complexity: 262

Purity/Quality:

97% ^*data from raw suppliers

Methyl 2-hydroxy-5-methyl-3-nitrobenzoate 95.0% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CC(=C(C(=C1)[N+](=O)[O-])O)C(=O)OC

Technology Process of Methyl 2-hydroxy-5-methyl-3-nitrobenzoate

There total 3 articles about Methyl 2-hydroxy-5-methyl-3-nitrobenzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

methanol (67-56-1) + 2-hydroxy-5-methyl-3-nitro-benzoic acid (59672-93-4) → methyl 2-hydroxy-5-methyl-3-nitrobenzoate (67191-44-0)

Guidance literature:

With sulfuric acid; at 0 - 85 ℃; for 16h;

Reference yield:

sulfuric acid (7664-93-9) + 2-hydroxy-5-methyl-3-nitro-benzoic acid (59672-93-4) → methyl 2-hydroxy-5-methyl-3-nitrobenzoate (67191-44-0) + 2-hydroxy-5-methyl-3-nitro-benzoic acid ethyl ester (70978-43-7)

Guidance literature:

In ethanol;

Reference yield:

5-Methylsalicylic acid (89-56-5) → methyl 2-hydroxy-5-methyl-3-nitrobenzoate (67191-44-0)

Guidance literature:

Multi-step reaction with 2 steps

1: 95 percent / sulfuric acid / 24 h / Heating

2: 72 percent / nitric acid / H₂O / 24 h / 20 °C

With sulfuric acid; nitric acid; In water;

DOI:10.1016/j.tet.2005.06.042

upstream raw materials:

methanol

2-hydroxy-5-methyl-3-nitro-benzoic acid

5-Methylsalicylic acid

sulfuric acid

Downstream raw materials:

2-hydroxy-5-methyl-3-nitrobenzenemethanol

2-hydroxy-5-methyl-3-(1⁽²⁾H-tetrazole-5-carbonylamino)-benzoic acid methyl ester

3-(1-benzyl-1H-tetrazole-5-carbonylamino)-2-hydroxy-5-methyl-benzoic acid methyl ester

N-(3-carboxy-2-hydroxy-5-methylphenyl)-1H-tetrazole-5-carboxamide

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 67191-44-0 Methyl 2-hydroxy-5-methyl-3-nitrobenzenecarboxylate

Send

Send

Metric Ton KG G Pound L ML

Send

Send