6,7-DICHLORO-1-TETRALONE

Base Information

• Chemical Name: 6,7-DICHLORO-1-TETRALONE
• CAS No.: 25095-57-2
• Molecular Formula: C10H8 Cl2 O
• Molecular Weight: 215.08
• Hs Code.: 2914700090
• Mol file: 25095-57-2.mol

Synonyms:6,7-Dichloro-1-tetralone;NSC 210434

Chemical Property of 6,7-DICHLORO-1-TETRALONE

Chemical Property:

• Vapor Pressure: 4.85E-05mmHg at 25°C
• Melting Point: 95 °C
• Boiling Point: 349°Cat760mmHg
• Flash Point: 147.4°C
• PSA: 17.07000
• Density: 1.372g/cm³
• LogP: 3.51240
• Storage Temp.: Sealed in dry,Room Temperature
• Solubility.: Acetonitrile (Slightly), Chloroform (Slightly)

Purity/Quality:

99%, ^*data from raw suppliers

6,7-Dichloro-1-tetralone ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 6,7-DICHLORO-1-TETRALONE

There total 6 articles about 6,7-DICHLORO-1-TETRALONE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 36.0%

4-(3,4-dichlorophenyl)butanoic acid (25157-66-8) → 6,7-dichloro-1,2,3,4-tetrahydro-naphthalen-1-one (25095-57-2)

Guidance literature:

With PPA;

DOI:10.1080/00397919108019786

Reference yield:

3-(3,4-dichlorobenzoyl)-propionic acid (50597-19-8) → 6,7-dichloro-1,2,3,4-tetrahydro-naphthalen-1-one (25095-57-2)

Guidance literature:

Multi-step reaction with 2 steps

1: N₂H₄, KOH / ethane-1,2-diol

2: polyphosphoric acid

With potassium hydroxide; PPA; hydrazine; In ethylene glycol;

DOI:10.1021/jm00295a022

Reference yield:

1,2-dichloro-benzene (95-50-1) → 6,7-dichloro-1,2,3,4-tetrahydro-naphthalen-1-one (25095-57-2)

Guidance literature:

Multi-step reaction with 3 steps

1: AlCl₃

2: N₂H₄, KOH / bis-(2-hydroxy-ethyl) ether

3: polyphosphoric acid

With potassium hydroxide; aluminium trichloride; PPA; hydrazine; In diethylene glycol;

DOI:10.1021/jm00284a002

upstream raw materials:

4-(3,4-dichlorophenyl)butanoic acid

Tributyl-(3,4-dichloro-phenyl)-stannane

3-(3,4-dichlorobenzoyl)-propionic acid

1,2-dichloro-benzene

Downstream raw materials:

(E)-2-(2-(7,8-dichloro-4,5-dihydronaphtho[1,2-d]-thiazol-2-yl)hydrazono)-3-(2-nitrophenyl)propanoic acid

(Z)-2-(2-(7,8-dichloro-4,5-dihydronaphtho[1,2-d]-thiazol-2-yl)hydrazono)-3-(2-nitrophenyl)propanoic acid

6,7-dichloro-3,4-dihydronaphthalen-1(2H)-one O-p-toluensulfonyl oxime

6,7-Dichloronaphthyl-1-acethydrazide