1(2H)-Quinolinecarboxylic acid, 4-[[(2R,3S)-3-amino-4-(3,5-difluorophenyl)-2-hydroxybutyl]amino]-6-(2,2 -dimethylpropyl)-3,4-dihydro-, phenylmethyl ester

Base Information

Chemical Name:1(2H)-Quinolinecarboxylic acid, 4-[[(2R,3S)-3-amino-4-(3,5-difluorophenyl)-2-hydroxybutyl]amino]-6-(2,2 -dimethylpropyl)-3,4-dihydro-, phenylmethyl ester
CAS No.:676136-58-6
Molecular Formula:C32H39F2N3O3
Molecular Weight:551.677
Hs Code.:

1(2H)-Quinolinecarboxylic acid,
4-[[(2R,3S)-3-amino-4-(3,5-difluorophenyl)-2-hydroxybutyl]amino]-6-(2,2
-dimethylpropyl)-3,4-dihydro-, phenylmethyl ester

Synonyms:

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Chemical Property of 1(2H)-Quinolinecarboxylic acid, 4-[[(2R,3S)-3-amino-4-(3,5-difluorophenyl)-2-hydroxybutyl]amino]-6-(2,2 -dimethylpropyl)-3,4-dihydro-, phenylmethyl ester

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Technology Process of 1(2H)-Quinolinecarboxylic acid, 4-[[(2R,3S)-3-amino-4-(3,5-difluorophenyl)-2-hydroxybutyl]amino]-6-(2,2 -dimethylpropyl)-3,4-dihydro-, phenylmethyl ester

There total 1 articles about 1(2H)-Quinolinecarboxylic acid, 4-[[(2R,3S)-3-amino-4-(3,5-difluorophenyl)-2-hydroxybutyl]amino]-6-(2,2 -dimethylpropyl)-3,4-dihydro-, phenylmethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 388071-27-0
tert-butyl (1S)-2-(3,5-difluorophenyl)-1-[(2S)-oxiranyl]ethylcarbamate

: 676136-56-4
4-amino-6-(2,2-dimethyl-propyl)-3,4-dihydro-2H-quinoline-1-carboxylic acid benzyl ester

: 676136-58-6
benzyl 4-{[(2R,3S)-3-amino-4-(3,5-difluorophenyl)-2-hydroxybutyl]amino}-6-neopentyl-3,4-dihydroquinoline-1(2H)-carboxylate

Guidance literature:: tert-butyl (1S)-2-(3,5-difluorophenyl)-1-[(2S)-oxiranyl]ethylcarbamate; 4-amino-6-(2,2-dimethyl-propyl)-3,4-dihydro-2H-quinoline-1-carboxylic acid benzyl ester; In isopropyl alcohol; at 60 - 90 ℃;

With hydrogenchloride; water; In diethyl ether; dichloromethane; for 2h;

With sodium hydroxide; In water; ethyl acetate;