NEOPENTYLZINC BROMIDE

Base Information

• Chemical Name: NEOPENTYLZINC BROMIDE
• CAS No.: 676137-12-5
• Molecular Formula: C5H11BrZn
• Molecular Weight: 216.436
• Mol file: 676137-12-5.mol

Synonyms:bromo(neopentyl)zinc;neopentylzinc(II) iodide;1-(1,1-Dimethylethoxy)-2,2-dimethylpropane;Neopentyl-tert.-butyl-ether;neopentylzinc bromide;Propane,1-(1,1-dimethylethoxy)-2,2-dimethyl;neopentylzinc(II) bromide;1-tert-Butoxy-2,2-dimethylpropane;

Chemical Property of NEOPENTYLZINC BROMIDE

Chemical Property:

• PSA: 0.00000
• LogP: -1.13190

Purity/Quality:

97% ^*data from raw suppliers

NEOPENTYLZINC BROMIDE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of NEOPENTYLZINC BROMIDE

There total 2 articles about NEOPENTYLZINC BROMIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2,2-dimethylpropyl bromide (630-17-1) + zinc (7440-66-6) → neopentyl zinc(II) bromide (676137-12-5)

Guidance literature:

With chloro-trimethyl-silane; tetra-(n-butyl)ammonium iodide; lithium chloride; In tetrahydrofuran; at 60 ℃; for 64h; Temperature; Time; Reagent/catalyst;

Reference yield:

→ neopentyl zinc(II) bromide (676137-12-5)

Guidance literature:

Reference yield: 91.0%

neopentyl zinc(II) bromide (676137-12-5) + 8-chloro-4-(3,5-dimethylphenyl)benzo[f]isoquinoline → 4-(3,5-dimethylphenyl)-8-neopentylbenzo[f]isoquinoline

Guidance literature:

With [1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene](3-chloropyridyl)palladium(ll) dichloride; lithium chloride; In tetrahydrofuran; 1-methyl-pyrrolidin-2-one; at 20 ℃; for 3h; Inert atmosphere;

upstream raw materials:

2,2-dimethylpropyl bromide

zinc

Downstream raw materials:

(S)-(3-neopentylpyridin-2-yl)(4-(trifluoromethyl)phenyl)-methanamine hydrochloride

4-fluoro-5-neopentylbenzene-1,2-diamine

Refernces

• 1、 -. "METHODS OF TREATMENT OF AMYLOIDOSIS USING BI-CYCLIC ASPARTYL PROTEASE INHIBITORS". Page/Page column 127. . Retrieved 2010/02/14.