1,3-Dimethoxy-10-methyl-9(10H)-acridinone

Base Information

• Chemical Name: 1,3-Dimethoxy-10-methyl-9(10H)-acridinone
• CAS No.: 13082-10-5
• Molecular Formula: C16H15NO3
• Molecular Weight: 269.2952
• DSSTox Substance ID: DTXSID30926926
• Nikkaji Number: J81.545D
• Wikidata: Q82901534
• Mol file: 13082-10-5.mol

Synonyms:1,3-Dimethoxy-10-methyl-9(10H)-acridinone;13082-10-5;1,3-Dimethoxy-10-methylacridone;1,3-dimethoxy-10-methylacridin-9-one;1,3-Dimethoxy-N-methylacridone;9(10H)-Acridinone, 1,3-dimethoxy-10-methyl-;9-Acridanone, 1,3-dimethoxy-10-methyl-;1,3-Dimethoxy-N-methyl-9-acridanone;1,3-dimethoxy-10-methylacridin-9(10H)-one;DTXSID30926926;1,3-dimethoxy-10-methyl-acridin-9-one;RD6-5073;1,3-Dimethoxy-10-methyl-10H-acridin-9-one;1,3-Dimethoxy-10-methyl-10-hydroacridin-9-one;1,3-Dimethoxy-10-methyl-9(10H)-acridinone #;1,3-DIMETHOXY-10-METHYL-9,10-DIHYDROACRIDIN-9-ONE

Chemical Property of 1,3-Dimethoxy-10-methyl-9(10H)-acridinone

Chemical Property:

• Vapor Pressure: 2.44E-08mmHg at 25°C
• Boiling Point: 451.4°Cat760mmHg
• Flash Point: 226.8°C
• PSA: 0.00000
• Density: 1.215g/cm³
• LogP: 0.00000
• XLogP3: 3.1
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 2
• Exact Mass: 269.10519334
• Heavy Atom Count: 20
• Complexity: 373

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CN1C2=CC=CC=C2C(=O)C3=C1C=C(C=C3OC)OC

Technology Process of 1,3-Dimethoxy-10-methyl-9(10H)-acridinone

There total 26 articles about 1,3-Dimethoxy-10-methyl-9(10H)-acridinone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

1,3-dimethoxy-10H-acridin-9-one (27221-40-5) + methyl iodide (74-88-4) → 1,3-dimethoxy-N-methylacridone (13082-10-5)

Guidance literature:

With sodium hydride;

DOI:10.1039/c39910001046

Reference yield: 79.0%

2,4-Dimethoxy-N,N-dimethyl-6-(methyl-phenyl-amino)-benzamide (83060-90-6) → 1,3-dimethoxy-N-methylacridone (13082-10-5)

Guidance literature:

With trifluoroacetic acid; for 60h; Heating;

DOI:10.1021/ja00384a064

Reference yield: 78.0%

3,5-dimethoxy-2-(trimethylsilyl)phenyl trifluoromethanesulfonate (1203549-54-5) + o-fluorobenzaldehyde N,N-dimethylhydrazone (455300-83-1) → 1,3-dimethoxy-N-methylacridone (13082-10-5)

Guidance literature:

3,5-dimethoxy-2-(trimethylsilyl)phenyl trifluoromethanesulfonate; o-fluorobenzaldehyde N,N-dimethylhydrazone; With cesium fluoride; In acetonitrile; at 65 ℃; for 10h;

With hydrogenchloride; water; In acetonitrile; at 100 ℃; for 2h;

With sodium methylate; In acetonitrile; at 100 ℃; for 2h;

DOI:10.1021/jo302378w

upstream raw materials:

N-methyl-1,3-dihydroxyacridone

dimethyl sulfate

1,3-dimethoxy-10H-acridin-9-one

9-chloro-1,3-dimethoxy-acridine

Downstream raw materials:

1,2,3-Trimethoxy-N-methylacridon