Cefamandole sodium salt

Base Information

Chemical Name:Cefamandole sodium salt
CAS No.:30034-03-8
Molecular Formula:C18H17N6NaO5S2
Molecular Weight:484.492
Hs Code.:
European Community (EC) Number:250-009-0
Mol file:30034-03-8.mol

Synonyms:CEFAMANDOLE SODIUM SALT;30034-03-8;sodium;(6R,7R)-7-[[(2R)-2-hydroxy-2-phenylacetyl]amino]-3-[(1-methyltetrazol-5-yl)sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate;SCHEMBL146171;SZKYIAIRBIWMNE-CFOLLTDRSA-N;AKOS030242255;7-[(2-hydroxy-2-phenylacetyl)amino]-3-[(1-methyltetrazol-5-yl)sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

Suppliers and Price of Cefamandole sodium salt

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
Cefamandole Sodium Salt
100mg
$ 403.00

TRC
CefamandoleSodiumSalt
1g
$ 605.00

Medical Isotopes, Inc.
CefamandoleSodiumSalt
100 mg
$ 860.00

ChemScene
Cefamandolesodium 98.07%
10mg
$ 70.00

Cayman Chemical
Cefamandole (sodium salt) ≥95%
25mg
$ 39.00

Cayman Chemical
Cefamandole (sodium salt) ≥95%
100mg
$ 140.00

Cayman Chemical
Cefamandole (sodium salt) ≥95%
50mg
$ 74.00

Cayman Chemical
Cefamandole (sodium salt) ≥95%
500mg
$ 390.00

Biosynth Carbosynth
Cefamandole sodium salt
100 mg
$ 250.00

Biosynth Carbosynth
Cefamandole sodium salt
50 mg
$ 160.00

Total 67 raw suppliers

Chemical Property of Cefamandole sodium salt

Chemical Property:

Appearance/Colour:White solid
Melting Point:>175 °C (dec.)
PSA：203.97000
LogP:-1.23150
Storage Temp.:Store at RT.
Solubility.:DMSO (Slightly), Methanol (Slightly), Water (Slightly)
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:10
Rotatable Bond Count:7
Exact Mass:485.06777932
Heavy Atom Count:32
Complexity:777

Purity/Quality:

99% ^*data from raw suppliers

Cefamandole Sodium Salt ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xn
Hazard Codes:Xn
Statements: 36/37/38-42/43
Safety Statements: 26-36

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN1C(=NN=N1)SCC2=C(N3C(C(C3=O)NC(=O)C(C4=CC=CC=C4)O)SC2)C(=O)O.[Na]
Isomeric SMILES:CN1C(=NN=N1)SCC2=C(N3[C@@H]([C@@H](C3=O)NC(=O)[C@@H](C4=CC=CC=C4)O)SC2)C(=O)O.[Na]
Description Cefamandole is a cephalosporin antibiotic that is effective against E. coli (MIC values range from 0.25-2 mg/L depending on strain) as well as H. influenza, S. pneumoniae, and S. aureus. It has been used to study the expression and inhibition of penicillin-binding proteins on bacterial cell walls and to study antibiotic resistance.
Uses Antibacterial;Bacterial transpeptidase inhibitor Broad-spectrum semi-synthetic cephalosporin antibiotic.

Technology Process of Cefamandole sodium salt

There total 2 articles about Cefamandole sodium salt which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 29169-64-0
D-2-phenyl-2-formyloxyacetyl chloride

: 24209-38-9
(6R,7R)-7-amino-3-[(1H-1-methyltetrazol-5-yl)thio]methylceph-3-em-4-carboxylic acid

: 30034-03-8
cefamandole sodium salt

Guidance literature:: D-2-phenyl-2-formyloxyacetyl chloride; (6R,7R)-7-amino-3-[(1H-1-methyltetrazol-5-yl)thio]methylceph-3-em-4-carboxylic acid; With N,O-bis-(trimethylsilyl)-acetamide; In ethyl acetate; at -10 - 35 ℃; for 1.5h;

With sodium isooctanoate; In ethanol; acetone; at 10 - 32 ℃; for 2h;