Benzyl {3-hydroxy-1-[methoxy(methyl)amino]-1-oxopropan-2-yl}carbamate

Base Information

Chemical Name:Benzyl {3-hydroxy-1-[methoxy(methyl)amino]-1-oxopropan-2-yl}carbamate
CAS No.:684270-34-6
Molecular Formula:C13H18N2O5
Molecular Weight:282.296
Hs Code.:
DSSTox Substance ID:DTXSID10694974
Mol file:684270-34-6.mol

Synonyms:SCHEMBL3709555;DTXSID10694974;684270-34-6;Benzyl {3-hydroxy-1-[methoxy(methyl)amino]-1-oxopropan-2-yl}carbamate

Suppliers and Price of Benzyl {3-hydroxy-1-[methoxy(methyl)amino]-1-oxopropan-2-yl}carbamate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
BENZYL-(S)-1-(N-METHOXY-N-METHYLCARBAMOYL)-2-HYDROXYETHYLCARBAMATE 95.00%
5MG
$ 501.38

Total 2 raw suppliers

Chemical Property of Benzyl {3-hydroxy-1-[methoxy(methyl)amino]-1-oxopropan-2-yl}carbamate

Chemical Property:

PSA：91.59000
LogP:0.49790
XLogP3:0.4
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:7
Exact Mass:282.12157168
Heavy Atom Count:20
Complexity:318

Purity/Quality:

85.0-99.8% ^*data from raw suppliers

BENZYL-(S)-1-(N-METHOXY-N-METHYLCARBAMOYL)-2-HYDROXYETHYLCARBAMATE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN(C(=O)C(CO)NC(=O)OCC1=CC=CC=C1)OC

Technology Process of Benzyl {3-hydroxy-1-[methoxy(methyl)amino]-1-oxopropan-2-yl}carbamate

There total 4 articles about Benzyl {3-hydroxy-1-[methoxy(methyl)amino]-1-oxopropan-2-yl}carbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 1145-80-8
N-(benzyloxycarbonyl)-L-serine

: 6638-79-5
N,O-dimethylhydroxylamine*hydrochloride

: 684270-34-6
benzyl N-[(1S)-1-(hydroxymethyl)-2-[methoxy(methyl)amino]-2-oxo-ethyl]carbamate

Guidance literature:: With 4-methyl-morpholine; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dichloromethane; at -10 ℃; for 2h;
DOI:10.1016/j.bmcl.2006.12.097

Reference yield: 82.0%

: 1145-80-8
N-(benzyloxycarbonyl)-L-serine

: 1117-97-1
N,0-dimethylhydroxylamine

: 684270-34-6
benzyl N-[(1S)-1-(hydroxymethyl)-2-[methoxy(methyl)amino]-2-oxo-ethyl]carbamate

Guidance literature:: With C₁₂H₆B₂Br₄O₃; In 1,2-dichloro-ethane; at 20 - 90 ℃; Reflux;
DOI:10.1055/s-0037-1610773

Reference yield: 81.0%

: 1676-81-9
N-benzyloxycarbonyl-L-serine methyl ester

: 6638-79-5
N,O-dimethylhydroxylamine*hydrochloride

: 684270-34-6
benzyl N-[(1S)-1-(hydroxymethyl)-2-[methoxy(methyl)amino]-2-oxo-ethyl]carbamate

Guidance literature:: With O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide;
DOI:10.1055/s-2004-817770