ETHYLENE GLYCOL DIBENZYL ETHER

Base Information

• Chemical Name: ETHYLENE GLYCOL DIBENZYL ETHER
• CAS No.: 622-22-0
• Molecular Formula: C16H18 O2
• Molecular Weight: 242.318
• Hs Code.: 2909309090
• Mol file: 622-22-0.mol

Synonyms:Ethane,1,2-bis(benzyloxy)- (7CI,8CI); 1,2-Bis(benzyloxy)ethane; 1,2-Dibenzyloxyethane;1,2-Ethanediol dibenzyl ether; Ethylene glycol dibenzyl ether; NSC 8915

Chemical Property of ETHYLENE GLYCOL DIBENZYL ETHER

Chemical Property:

• Vapor Pressure: 0.000166mmHg at 25°C
• Refractive Index: 1.5450-1.5480
• Boiling Point: 210 °C / 10mmHg
• Flash Point: 127.6°C
• PSA: 18.46000
• Density: 1,06 g/cm3
• LogP: 3.42000

Purity/Quality:

98%,99%, ^*data from raw suppliers

Ethylene Glycol Dibenzyl Ether ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of ETHYLENE GLYCOL DIBENZYL ETHER

There total 11 articles about ETHYLENE GLYCOL DIBENZYL ETHER which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

benzyl chloride (100-44-7) + ethylene glycol (107-21-1) → 1,2-dibenzyloxyethane (622-22-0)

Guidance literature:

With iron(III) perchlorate; at 100 ℃; for 0.5h; neat (no solvent);

DOI:10.1007/s00706-008-0054-x

Reference yield: 82.0%

2-Benzyloxyethanol (622-08-2,1201808-31-2) + C24H18F3NO2 → 1,2-dibenzyloxyethane (622-22-0)

Guidance literature:

With [(t-BuXPhos)Au]NTf₂; In 1,4-dioxane; at 50 ℃; for 25h; Reagent/catalyst; Solvent; Temperature; Molecular sieve;

DOI:10.1016/j.tetlet.2020.152233

Reference yield: 8.0%

benzyl bromide (100-39-0) + ethylene glycol (107-21-1) → 1,2-dibenzyloxyethane (622-22-0) + 2-Benzyloxyethanol (622-08-2,1201808-31-2)

Guidance literature:

With silver(l) oxide; In dichloromethane; for 15h; Ambient temperature;

DOI:10.1016/S0040-4039(97)01328-2

upstream raw materials:

benzyl chloride

ethylene glycol

benzyl bromide

2-phenyl-1,3-dioxolane

Downstream raw materials:

ethylene glycol

α-p-tolylbenzyl cation

α-o-tolylbenzyl cation

p-benzylbenzyl cation

Refernces

• 1、 -. "A method of manufacturing an alkylene glycol ether (poly)". Paragraph 0056; 0057. . Retrieved 2016/10/17.
• 2、 Sirkecioglu, Okan,Karliga, Bekir,Talinli, Naciye. "Benzylation of alcohols by using bis[acetylacetonato]copper as catalyst". . p. 8483 - 8485. Retrieved 2007/10/03.