2-Nitrobenzaldehyde phenyl hydrazone

Base Information

• Chemical Name: 2-Nitrobenzaldehyde phenyl hydrazone
• CAS No.: 610-64-0
• Molecular Formula: C13H11N3O2
• Molecular Weight: 241.249
• European Community (EC) Number: 667-139-2
• NSC Number: 64715
• Nikkaji Number: J96.212K
• Mol file: 610-64-0.mol

Synonyms:610-64-0;o-Nitrobenzaldehyde phenylhydrazone;MLS002693481;2-Nitrobenzaldehyde phenyl hydrazone;NSC64715;NSC-64715

Chemical Property of 2-Nitrobenzaldehyde phenyl hydrazone

Chemical Property:

• Vapor Pressure: 6.86E-07mmHg at 25°C
• Refractive Index: 1.608
• Boiling Point: 408.7 °Cat760mmHg
• Flash Point: 201 °C
• Density: 1.2 g/cm³
• XLogP3: 3.4
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 3
• Exact Mass: 241.085126602
• Heavy Atom Count: 18
• Complexity: 295

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)NN=CC2=CC=CC=C2[N+](=O)[O-]
• Isomeric SMILES: C1=CC=C(C=C1)N/N=C\C2=CC=CC=C2[N+](=O)[O-]

Technology Process of 2-Nitrobenzaldehyde phenyl hydrazone

There total 12 articles about 2-Nitrobenzaldehyde phenyl hydrazone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

phenylhydrazine (100-63-0) + 2-nitro-benzaldehyde (552-89-6) → 1-(2-nitrobenzylidene)-2-phenylhydrazine (610-64-0)

Guidance literature:

at 70 ℃; for 0.0833333h;

DOI:10.1002/jhet.267

Reference yield: 92.0%

phenylhydrazine (100-63-0) + 2-nitro-benzaldehyde (552-89-6) → (E)-1-(2-nitrobenzylidene)-2-phenylhydrazine (610-64-0)

Guidance literature:

With 1-deoxy-1-(methylamino)-D-glucitol; In ethanol; water; at 20 ℃; for 0.5h; Green chemistry;

DOI:10.1080/00397911.2016.1258476

Reference yield:

2-nitrobenzyl chloride (612-23-7) + phenylhydrazine (100-63-0) → 1-(2-nitrobenzylidene)-2-phenylhydrazine (610-64-0)

Guidance literature:

With ethanol;

upstream raw materials:

2-nitrobenzyl chloride

phenylhydrazine

o-nitrobenzaldehyde semicarbazone

acetic acid

Downstream raw materials:

N'-(2,4-dibromo-phenyl)-2-nitro-benzohydrazonoyl bromide

nitrin

N-(2-Nitro-α-phenylazobenzyl)hydrazin-N,N'-dicarbonsaeurediethylester

14-(2-nitrophenyl)-14H-dibenzo[a,j]xanthene

Refernces

• 1、 Panda, Niranjan,Ojha, Subhadra. "Facile synthesis of pyrazoles by iron-catalyzed regioselective cyclization of hydrazone and 1,2-diol under ligand-free conditions". . p. 244 - 251. Retrieved 2018/03/13.
• 2、 Zhang, Mo,Shang, Ze-Ren,Li, Xiao-Tang,Zhang, Jia-Nan,Wang, Yong,Li, Kang,Li, Yang-Yang,Zhang, Zhan-Hui. "Simple and efficient approach for synthesis of hydrazones from carbonyl compounds and hydrazides catalyzed by meglumine". . p. 178 - 187. Retrieved 2017/01/10.