1-(2-Hydroxyethoxy)methyl-5-methyluracil

Base Information

Chemical Name:1-(2-Hydroxyethoxy)methyl-5-methyluracil
CAS No.:68724-11-8
Molecular Formula:C8H12N2O4
Molecular Weight:200.194
Hs Code.:2933599090
Mol file:68724-11-8.mol

Synonyms:1-[(2-OHEtO)Me]T;1-[(2-hydroxyethoxy)methyl]-5-methyl-2,4(1H,3H)-pyrimidinedione;1-(2-hydroxyethoxymethyl)-5-methyl-pyrimidine-2,4-dione;1-<(2-hydroxyethoxy)methyl>-5-methyluracil;1-((2-hydroxyethoxy)methyl)-5-methylpyrimidine-2,4(1H,3H)-dione;acyclothymidine;5-methyl-1-(2'-hydroxyethoxymethyl)uracil;1-<(2-hydroxyethoxy)methyl>thymine;

Suppliers and Price of 1-(2-Hydroxyethoxy)methyl-5-methyluracil

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
1-((2-Hydroxyethoxy)methyl)-5-methylpyrimidine-2,4(1H,3H)-dione 95+%
5g
$ 707.00

Chemenu
1-((2-hydroxyethoxy)methyl)-5-methylpyrimidine-2,4(1H,3H)-dione 95%
5g
$ 668.00

American Custom Chemicals Corporation
1-(2-HYDROXYETHOXY)METHYL-5-METHYLURACIL 95.00%
1G
$ 555.45

AHH
1-(2-Hydroxyethoxy)methyl-5-methyluracil 98%
1g
$ 198.00

Total 19 raw suppliers

Chemical Property of 1-(2-Hydroxyethoxy)methyl-5-methyluracil

Chemical Property:

Boiling Point:°Cat760mmHg
Flash Point:°C
PSA：84.32000
Density:1.285g/cm³
LogP:-1.18860
Storage Temp.:2-8°C(protect from light)

Purity/Quality:

99.0% ^*data from raw suppliers

1-((2-Hydroxyethoxy)methyl)-5-methylpyrimidine-2,4(1H,3H)-dione 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

General Description 1-(2-Hydroxyethoxy)methyl-5-methyluracil (also known as acyclothymidine) is a pyrimidine-derived compound that has been studied for its potential antiviral and antitumor properties. While it showed no significant activity against orthopoxviruses (e.g., vaccinia and cowpox viruses) or other DNA/RNA viruses, it demonstrated potent inhibitory effects on the enzymatic degradation of 5-fluoro-2'-deoxyuridine (FUdR), enhancing the antitumor efficacy of FUdR esters when administered orally in combination. Additionally, structurally related derivatives have been synthesized as inhibitors against drug-resistant HIV mutants, indicating its potential in antiviral drug development.

Technology Process of 1-(2-Hydroxyethoxy)methyl-5-methyluracil

There total 11 articles about 1-(2-Hydroxyethoxy)methyl-5-methyluracil which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%