TESTOSTERONE ENOL DIACETATE

Base Information

• Chemical Name: TESTOSTERONE ENOL DIACETATE
• CAS No.: 1778-93-4
• Molecular Formula: C23H32O4
• Molecular Weight: 372.505
• Mol file: 1778-93-4.mol

Synonyms:TESTOSTERONE ENOL DIACETATE;

Chemical Property of TESTOSTERONE ENOL DIACETATE

Chemical Property:

• Vapor Pressure: 1.26E-09mmHg at 25°C
• Melting Point: 143-145 °C
• Boiling Point: 486.7°Cat760mmHg
• Flash Point: 239.3°C
• PSA: 52.60000
• Density: 1.14g/cm³
• LogP: 4.93780

Purity/Quality:

97% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Controlled substance.

Technology Process of TESTOSTERONE ENOL DIACETATE

There total 14 articles about TESTOSTERONE ENOL DIACETATE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

testosterone (58-22-0) + acetyl chloride (75-36-5) → testosterone enol diacetate (1778-93-4)

Guidance literature:

With pyridine; acetic anhydride; for 3.5h; Reflux;

DOI:10.1080/00397910802618430

Reference yield: 70.0%

testosterone (58-22-0) + acetic anhydride (108-24-7) + acetyl chloride (75-36-5) → testosterone enol diacetate (1778-93-4)

Guidance literature:

at 100 ℃; for 2h;

DOI:10.1002/chem.202001120

Reference yield:

testosterone (58-22-0) + acetic anhydride (108-24-7) → testosterone enol diacetate (1778-93-4)

Guidance literature:

With acetyl chloride;

DOI:10.1007/BF01491541

upstream raw materials:

Isopropenyl acetate

testosterone acetate

testosterone

potassium acetate

Downstream raw materials:

Acetic acid (10R,13S,17S)-6-fluoro-10,13-dimethyl-3-oxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl ester

17β-acetoxy-6β-fluoro-4-androsten-3-one

17β-acetoxy-6α-fluoro-4-androsten-3-one

(5S,8R,9S,10S,13S,14S,17S)-10,13-dimethyl-4,5,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene-3,17-diyl diacetate

Refernces

• 1、 Westphal. "-". . . Retrieved 1937.
• 2、 Rozatian, Neshat,Harsanyi, Antal,Murray, Ben J.,Hampton, Alexander S.,Chin, Emily J.,Cook, Alexander S.,Hodgson, David R. W.,Sandford, Graham. "Kinetics of Electrophilic Fluorination of Steroids and Epimerisation of Fluorosteroids". supporting information. p. 12027 - 12035. Retrieved 2020/08/28.